ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1975.tb00941.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTHidroacanthoma simplex is a rare tumor and its histogenesis and classification have been the subject of discussion, especially as to its relation to eccrine poroma. The tumor in this study developed on the knee of an old woman as a Bowen's disease‐like lesion. Clinical and histological examinations confirmed the diagnosis of hidroacanthoma simplex.Ultrastructurally, the tumor cells revealed a structure similar to that of eccrine poroma as regards numerous glycogen granules and the ring‐shaped distribution of tonofilaments, but different from eccrine poroma in having no intracellular cavity formation and underdeveloped tonofilaments and desmosomes. These findings indicate that hidroacanthoma simplex is related to eccrine poroma, but is not identical to it nor an intraepidermal form of

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1975.tb00942.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTSix patients with erythropoietic protoporphyria, the most common of the porphyrias, were seen at Nagasaki University Hospital and studied clinically and histopathologically. Cutaneous changes were observed in all six patients and are considered to be the result of both protoporphyrin and sunlight. These changes were classified as either acute or chronic, and the chronic changes were examined histologically and revealed a perivascular accumulation of PAS positive material in the upper dermis.Slight aberrations of liver function were found in three of our six cases, and we suggest that the liver cells were involved by a combination of protoporphyrin and sunlight.

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1975.tb00943.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTElectron microscopic examinations were performed on skin specimens obtained from six patients with erythropoietic protoporphyria and one patient with erythropoietic porphyria (Günther).The most important histopathological findings in the involved skin of porphyria is an accumulation of PAS positive material surrounding the small vessels in the upper dermis. The electron microscopic features of this material are discussed. It is not clear how this material is produced

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1975.tb00944.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTAntibodies against the cytoplasm of normal human epidermal cells were found in both a newborn baby with incontinentia pigmenti and in her normal mother. These antibodies showed no tissue or species specificity as in the case of anti‐nuclear antibodies in SLE. The antibodies were assayed by indirect immunofluorescence. The antibody titer in the serum of the baby gradually decreased over a period of months while the mother's titer remained high. The generalized vesiculo‐bullous eruption noted at birth subsided with the decrease of antibody titer. The immunoglobulin class of the antibodies was determined to be IgG, which passes through the placental barrier.It is suggested that the anti‐cytoplasmic antibodies produced by some unknown cause in pregnant women could be transferred to the baby and induce a variety of diso

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1975.tb00945.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTAcidic nuclear proteins and histories were extracted from isolated nuclei of human lymphocytes cultured in media both with and without phytohemagglutinin, and their amounts were measured according to Folin‐Lowry's technique. The ratio of the amount of acidic nuclear proteins to histones was calculated in each case. The ratio of nuclear proteins from lymphocytes cultured in media with phytohemagglutinin was higher than that from lymphocytes cultured in media without phytohemagglutinin. It is suggested that acidic nuclear proteins might restore histone‐inhibited DNA‐dependent RNA synthesis in human lymphocytes activated by phytohemagglu

ISSN:0385-2407    

DOI:10.1111/j.1346-8138.1975.tb00946.x

年代:1975

数据来源: WILEY