摘要:

The enzyme ‘true’ cholinesterase is connected to the membrane of the erythrocytes and reacts selectively on acetylcholine. There is no evidence to suggest that this substrate is present in the erythrocytes, but acetylcholine is found in the spleen without the existence of true cholinesterase. Erythrocytes remain in the sinus of the spleen for several hours. Perhaps the cholinesterase connected to erythrocytes could be the enzyme for the acetylcholine in the spleen and possibly the enzyme system could have an effect on the erythrocytes during prolonged residence in the spleen.In the course of in vitro experiments it has been illustrated that acetylcholine in an environment of erythrocytes can develop haemolysis and that it is acetic acid released during the enzymatic reaction that has the haemolytic effect.The question is posed whether the increased H+‐ion activity, which has been established relating to erythrocytes from the spleen, can be connected with the enzyme system acetylcholine‐choline

ISSN:0036-553X    

DOI:10.1111/j.1600-0609.1986.tb00859.x

出版商:Blackwell Publishing Ltd    

年代:1986

数据来源: WILEY