ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

We reviewed our experience with patients with symptoms of dysphagia to determine whether endoscopy increased the chance of finding esophageal carcinoma when barium studies of the esophagus were normal. Endoscopy reports from 1974 to 1982 identified 195 patients with x-ray-negative dysphagia. In no patient was esophageal carcinoma found endoscopically. When patients with hiatal hernia (22) or endoscopic Grade I or II esophagitis (52) were excluded, only eight patients were found to have an endoscopic abnormally not demonstrated previously by x-ray. In addition, 56 cases of esophageal carcinoma seen at our institution over the same period all showed abnormal barium esophagrams at the time of presentation. We conclude that endoscopy to exclude esophageal carcinoma in patients with dysphagia is not as necessary as claimed, at least when adequste barium studies of the esophagus are normal.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

We define “giant” gastric ulcer as a chronic gastric ulcer, with a diameter ≥ 3 cm. Treatment of inpatients with several conventional antiulcer agents resulted in significantly lower healing rates in giant gastric ulcer than in “large” (15 < &thetas; 30 mm) or “medium” (5 < &thetas; ≤ 15 mm) ulcers. In 48 patients with giant gastric ulcers treated with ranitidine, cumulative endoscopic healing rates were: 0% after 2 weeks, 16.7% after 4 weeks, 50.0% after 6 weeks, 77.1% after 8 weeks, 85.4% after 10 weeks, and 87.5% after 12 weeks of treatment. Corresponding healing rates were determined for the control group, which included patients treated with various conventional antiulcer agents. Comparison of these results revealed that from the fourth week of treatment onward, healing rates of the ranitidine group were significantly higher than those of the control group. There was little difference in the cumulative healing rates in the ranitidine group. From these results, ranitidine is considered to be useful in the treatment of giant gastric ulcer.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

We determined the types of pancreatobiliry ductal anatomy in 58 chronic alcoholic patients with and without pancreatitis at ERCP. Twenty-four of 28 patients (86%) with pancreatitis had separately opening common bile ducts and pancreatic ducts, while only six of 30 patients (20%) without pancreatitis had this finding. We conclude that a separate channel configuration is an inherited predisposing factor to alcoholic pancreatitis. As both chronic alcohol ingestion and separately opening bile and pancreatic ducts have been associated with ductal epithelial hyperplasia, the pathogenesis of alcoholic pancreatitis may be hy way of duct obstruction produced by cell hyperplasia.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

There is a variable temporal relationship between the presenting symptoms of inflammatory bowel disease and associated hepatic disease: hepatobiliary disease may precede, occur with, or occur many years after the onset of the bowel disease. We describe six patients in whom bepatobiliary disease of initially obscure origin preceded the development of inflammatory bowel disease. The colitis which subsequently developed in these patients was symptomatically mild. In our series, there was a high prevalence of sclerosing cholangitis. We conclude that in patients with chronic hepatobiliary disease of obscure origin, evaluation should include detailed questioning about bowel symptoms and routine sigmoidoscopy to screen for subclinical colitis. if a diagnosis of colitis is made in such a patient, endoscopic retrograde cholangiography may be indicated to evaluate the biliary tree for sclerosing cholangitis.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

The study was aimed both at defining normal values of pancreatic function and at looking at variables (age, sex, body weight, height, and body surface) which may influence the range of normality in 271 normal controls evaluated consecutively by duodenal intubation from 1974 to 1981. Frequency distribution of all functional values were consistent with a Gaussian curve. A positive, linear correlation was found between secretory parameters and both volume secretion and output values, while no correlation was detected with bicarbonate and enzymes values. Duodenal fluid secretion and both bicarbonate and enzymes output were approxiately 20% higher in males than in females, the difference being statistically significant. Mean values of both bicarbonate and enzyme concentration were not statistically different between sexes. When related to body surface, both volume and outputs values in males were no more different from those observed in females.The study has shown that body size influences pancreatic functional values and, therefore, the values should be related to some parameters of body size as body surface. The difference between males and females in fluid secretion and output values is linked primarily to differences in body size. The normal distribution of all functional parameters implies that normal limits may be calculated with standard parametric statistical analysis.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

Apathetic thyrotoxicosis is frequently difficult to recognize and can imitate a variety of diseases. A patient with a severe thyrotoxic state is reported, who presented with protracted epigastic pain and vomiting. Hyperthyroidism should be considered in patients with such prolonged and unexplained symptoms.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

A 69-year old woman suffered from severe dysphagia, abdominal pain, and weight loss. The dysphagia was accompanied by nasal speech, nasal regurgitation of food, weakness, and wasting of the proximal muscles of the upper and lower girdles. Laboratory data revealed T3 sephadex uptake 65.2%; T4 15.1 mcg %; and T3 250 ng%. Treatment with antithyroid medication reversed the manifestation of all the symptoms, including dysphagia. Cine-studies revealed esophageal motor dysfunction as the cause of the dysphagia. Hyperthyroidism is a rare, but treatable cause of unexplained dysphagia.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

A 54-year-old man developed basal cell carcinoma of the anal verge. This extremely rare tumor behaves rather innocently, whereas cloacogenic carcinoma of the anus, which resembles it histologically, metastasizes early and often proves fatal. Clinical and histopathologic characteristics of the two anal neoplasms are tabulated to facilitate differential diagnosis, and thereby promote their very different therapies.

ISSN:0192-0790    

出版商:OVID    

年代:1984

数据来源: OVID