ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Several techniques are available today to access the bile ducts, all equally safe and effective. Since 1990, we have studied three groups of patients treated with different methods: the sequential endoscopic sphincterotomy + laparoscopic cholecystectomy, the single-stage laparoscopic approach, and the single laparoscopic-endoscopic approach.The results obtained in 127 patients to date suggest that one single-stage treatment is more convenient for the patient, while the combination of endoscopic sphincterotomy with laparoscopic cholecystectomy is preferable in terms of efficacy and safety.

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Achalasia is an uncommon motility disorder of the esophagus with an uncertain etiology. Considerable debate exists regarding the most effective treatment for long-term relief of symptoms. For decades, pneumatic dilatation has been the primary treatment option, and surgery was reserved for patients who required repeated dilations or for those who were not willing to undergo the risk of perforation associated with dilatation. Recently botulinum toxin injection of the lower esophageal sphincter has been shown to provide substantial short-term relief from dysphagia; however, its effect only lasts for a short period of time. Recently, minimally invasive surgical techniques have been developed to perform a Heller myotomy effectively with an antireflux procedure. This has become a primary treatment option for many patients. We present a review of the outcome of different therapeutic options of achalasia with a special focus on laparoscopic procedures.

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Lactose malabsorption and lactase deficiency are chronic organic pathologic conditions characterized by abdominal pain and distention, flatulence, and the passage of loose, watery stools. Though malabsorption of the sugar lactose is determinable by breath hydrogen test or jejunal biopsy, intolerance can only be confirmed by challenge with lactose-containing food, the response to which may not be immediate. The difficulty of making a positive diagnosis of these conditions has led to a proportion of lactose-intolerant patients being misdiagnosed with irritable bowel syndrome (IBS), which has a remarkably similar symptom complex and for which there is no current pathophysiologic marker. The incidence of the two disorders is approximately equal, but the actual proportion of patients with IBS incorrectly diagnosed in this way varies as a function of the methodology used. Once correct diagnosis is established, introduction of a lactose-free dietary regime relieves symptoms in most patients. Symptom similarity and the resultant incorrect diagnosis of IBS may explain the refractory nature of some patients labeled as IBS who remain largely unaware of the relationship between food intake and symptoms.

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

The large number of endoscopies and endoscopic reports produced in the United States represents a large repository of clinical data. However, reports are highly variable in content and structure and therefore cannot be used to create clinical databases. The introduction of automated endoscopic reporting systems should permit database creation only if acceptable standards for the structure and content of the report are developed. The structure of an endoscopic report is the framework in which the specific details of the endoscopy can be recorded. The basic components can consist of the following: Patient, Visit, Study, Result, Diagnosis, and Recommendation. Precise definition of each of these components requires consensus on what the minimum included elements should be. Experience with the Minimal Standard Terminology indicates that it is possible to create a broadly acceptable lexicon of descriptive endoscopic terms which can be included as a Result. The systematic development of the structure and content of endoscopic reports is mandatory before it is possible to create large, clinically useful databases of endoscopic reports.

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

The cause of diffuse esophageal spasm (DES) has not been clearly established, and effective treatment is lacking. To determine whether a psychosomatic approach can be effective in treating DES patients, nine patients and 26 healthy volunteers were studied. Esophageal manometry and psychological testing were performed in both groups. The psychological background of the DES patients was investigated. Psychiatric diagnoses were made according to the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders, 3rd edition, revised. The authors started psychosomatic treatment with isosorbide dinitrate for 1 month, then prescribed serotonin reuptake inhibitor antidepressants for an additional month. Anxiety and depression scores were substantially higher for the DES group than for the control group. Five of the nine DES patients (56%) were diagnosed as having major psychiatric disorders. Only one patient showed improvement with isosorbide dinitrate, and eight patients improved with antidepressants. These initial observations suggest that psychosomatic treatment with antidepressants may be effective in the treatment of DES.

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

The authors studied the relationship of endoscopic esophagitis and gastroesophageal flap valve (GEFV) in patients with symptomatic gastroesophageal reflux (GER). On endoscopy, the GEFV was graded as I to IV in 138 patients with acid regurgitation and heartburn relieved by antacids, and in 54 control subjects without symptoms suggestive of GER. Grade of GEFV was correlated with the grade of esophagitis, response to medical treatment, duration of symptoms, obesity, smoking, sex, and age of the patient. Abnormal GEFV (grades III and IV) was more frequent in patients with symptomatic GER, both with and without esophagitis, compared with control subjects (p= 0.000001,p= 0.03). Abnormal GEFV was significantly more common in patients with GER with esophagitis compared with those without (p< 0.00001). There was no significant difference in the distribution of normal and abnormal GEFV in patients with grade 1 esophagitis. However, grade 2 and grade 3 esophagitis were associated more commonly with an abnormal GEFV (p< 0.00001,p< 0.02 respectively). Hiatal hernia is always associated with an abnormal GEFV. Abnormal GEFV correlated significantly with age (more frequent when older than 40 years). Sex, duration of symptoms (>3 years), response to medical therapy, smoking, and obesity (body mass index > 30 kg/m2) did not correlate significantly with abnormal GEFV. We conclude that endoscopic esophagitis is usually associated with abnormal GEFV. It is more frequent in grades 2 and 3 but not grade 1 esophagitis. It is also encountered more commonly after the age of 40 years.

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

The clinical recognition ofHelicobacter pylorigastritis in children with recurrent abdominal pain is difficult. We assessed the value of a simplified13C urea breath test (13C-UBT) in a selected group of children with nocturnal waking and disruptive recurrent abdominal pain who fulfilled criteria for endoscopy. Gastric antral biopsies were examined histologically and by the quick urease test and were compared withH. pyloriserology and the13C-UBT in a prospective study of 50 children referred to a tertiary center. Thirty-two patients had gastritis and of these, 19 had histologically provenH. pylorigastritis. Seventeen of these 19 patients had a positive13C-UBT. The sensitivity and specificity of the13C-UBT compared with the histologic diagnosis ofH. pyloriwas 89 and 90% respectively. The13C-UBT was more specific than theH. pyloriserology. The13C-UBT using two breath collections is a reliable and noninvasive diagnostic test forH. pyloriinfection in children.

ISSN:0192-0790    

出版商:OVID    

年代:1999

数据来源: OVID