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| 1. |
Extending public health surveillance of HIV disease |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page 2061-2064
S. M. Gore,
V. T. Farewell,
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ISSN:0277-6715
DOI:10.1002/sim.4780122202
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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| 2. |
Extending public health surveillance of HIV infection: Information from a five cohort workshop |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page 2065-2085
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ISSN:0277-6715
DOI:10.1002/sim.4780122203
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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| 3. |
Markers as time‐dependent covariates in relative risk regression |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page 2087-2098
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PDF (765KB)
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ISSN:0277-6715
DOI:10.1002/sim.4780122204
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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| 4. |
Marker paths |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page 2099-2126
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PDF (1570KB)
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ISSN:0277-6715
DOI:10.1002/sim.4780122205
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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| 5. |
Markov models |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page 2127-2130
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PDF (240KB)
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ISSN:0277-6715
DOI:10.1002/sim.4780122206
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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| 6. |
Tracking of markers and onset of disease among HIV‐1 seroconverters |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page 2133-2145
Noya Galai,
Alvaro Muñoz,
Kan Chen,
Vincent J. Carey,
Joan Chmiel,
Susan Y. J. Zhou,
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摘要:
AbstractRepeated measurements on persons infected with HIV‐1 indicate that infection has a dynamic impact on several markers of immune suppression and activation. The objectives of this report are: )a( to provide a statistical model for the correlation structure of serial measurements of immunological markers, and )b( to identify features of marker profiles associated with the timing of AIDS diagnoses. We analyse data obtained from 328 seroconverters participating in the Multicenter AIDS Cohort Study on whom the date of HIV‐1 seroconversion is known within ∓ 4·5 months. Immunological markers considered here are CD4 cell counts, serum β2‐microglobulin and serum neopterin. The statistical model for HIV‐related changes in markers consists of )1( a piecewise linear regression model for the trajectories of markers over time and )2( a two‐parameter autocorrelation function that generalizes Markovian and simple random effects autocorrelation structures. Application of this model for marker measurements revealed a high degree of tracking, as the estimated autocorrelation function exhibited sub‐exponential decay over time. Though current marker levels are most informative on future values, there is substantial information )memory( in previous measurements. A feature suggested by the analysis of groups formed according to the length of the AIDS‐free period, is the sequential divergence of the CD4 trajectories where steeper declines occurred with a two‐year lag prior to AIDS onset. For AIDS cases diagnosed 3–5 and 5–7 years after seroconversion, the rates of decline compared with those free of AIDS for at least 4 years were steeper by 95 and 46 per cent respectively at
ISSN:0277-6715
DOI:10.1002/sim.4780122207
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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| 7. |
A random effects model for ordinal responses from a crossover trial. by F. Ezzet and J. Whitehead, Statistics in Medicine, 10, 901–907 )1991( |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page 2147-2151
Stephen Senn,
Farkad Ezzet,
John Whitehead,
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ISSN:0277-6715
DOI:10.1002/sim.4780122208
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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| 8. |
Masthead |
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Statistics in Medicine,
Volume 12,
Issue 22,
1993,
Page -
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PDF (77KB)
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ISSN:0277-6715
DOI:10.1002/sim.4780122201
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1993
数据来源: WILEY
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