ISSN:1076-2752    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

Toinvestigate the association between organic solvent exposure and menstrualdisturbance, we conducted a cross-sectional study among 1408 petrochemicalworkers in China. Based on an industrial hygiene evaluation, we classified theworkshops according to the presence or absence of organic solvents (benzene,styrene, toluene, or xylene). We used logistic regression to estimate oddsratios and 95% confidence intervals for prolonged menstrual cycle length(oligomenorrhea: average cycle length >35 days during the previous year)associated with the exposure. After adjustment for confounders, eachadditional year of work in an exposed workshop was associated with a 7%increase in oligomenorrhea (odds ratio, 1.07; 95% confidence interval, 1.00 to1.14). Compared with no exposure, 3 or more years of exposure was associatedwith a 53% increase in oligomenorrhea (odds ratio, 1.53; 95% confidenceinterval, 1.00 to 2.34). We concluded that exposure to organic solvents isassociated with a trend toward increased frequency ofoligomenorrhea.

ISSN:1076-2752    

出版商:OVID    

年代:2001

数据来源: OVID

ISSN:1076-2752    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

Inthis cross-sectional study, the prevalence of acute and chronic respiratorysymptoms and lung function were investigated in 236 (169 male and 67 female)livestock farmworkers raising domestic animals, including cattle and horses.The prevalence of acute and chronic respiratory symptoms was recorded byadministering a modified version of the British Medical Research Councilquestionnaire on respiratory symptoms. Lung function was measured by recordingthe maximum expiratory flow-volume curves from which the forced vitalcapacity, the one-second forced expiratory volume, and the maximum expiratoryflow rates at 50% and the last 25% were measured. There was a significantlyhigher prevalence of almost all chronic respiratory symptoms in farmerscompared with controls: highest among men for chronic cough (27.2%) andhighest among women for dyspnea (28.3%). Typical symptoms of occupationalasthma were diagnosed in 3.6% of the male and 1.5% of the female livestockfarmers. A logistic regression analysis performed on chronic respiratorysymptoms of livestock workers indicate significant effects of smoking(P< 0.001) on all symptoms exceptoccupational asthma. A large number of male and female livestock farmworkerscomplained of acute work-related symptoms: highest for dry cough (52.2%) andshortness of breath (44.9%). Lung function data among these workersdemonstrated a trend toward lower lung function in general. Multivariateanalysis of lung function parameters indicate significant effects of length ofemployment and smoking in male and length of employment in female livestockfarmworkers. The data suggest that employment in livestock farming may beassociated in a dose-dependent manner with the development of acute andchronic respiratory symptoms and lung functionchanges.

ISSN:1076-2752    

出版商:OVID    

年代:2001

数据来源: OVID

ISSN:1076-2752    

出版商:OVID    

年代:2001

数据来源: OVID

ISSN:1076-2752    

出版商:OVID    

年代:2001

数据来源: OVID