摘要:

This is a retrospective report of 54 patients with the diagnosis of Wilms’ tumor treated at Roswell Park Memorial Institute from 1946 to 1977. The age ranged from 1 month to 57 years with a mean of 7.2 years and a median of 5 years. An analysis of the survival results showed that patients continued to die of disease until 66 months post-diagnosis, making the 5-year survival a much better evaluation criterion for this group than the traditional 2-year survival. Males fared significantly better in this series (p < 0.01). This was not due to detectable differences in age group, or histology. While the older age group (more than 15 years old) showed a somewhat better survival outlook for the first 2 years post-diagnosis, this difference became negligible at 5 years post-diagnosi

ISSN:0030-2414    

DOI:10.1159/000225604

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Ascites is a common manifestation of solid tumors, but is unusual secondary to reticuloendothelial and lymphoproliferative malignancies. This report describes a case of chronic lymphocytic leukemia whose relapse was heralded by splenomegaly with massive ascites. A 2,750 g spleen was removed which showed extensive infiltration with lymphocytes. The portal areas of the liver were similarly infiltrated. This hepatic and splenic involvement most likely produced portal hypertension which resulted in ascites. The formation of ascites in such patients heralds a short survival, since it is probably one of the manifestations of the accelerated form of the disease.

ISSN:0030-2414    

DOI:10.1159/000225605

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

3β-Hydroxy-13α-amino-13,17-seco-5-androsten-17-oic-13,17-lactam p-N, N-bis-(2-chloroethyl)-amino phenylacetate gives results in P388 and L1210 leukemias in mice, by the intraperitoneal route of administratio

ISSN:0030-2414    

DOI:10.1159/000225606

出版商:S. Karger AG    

年代:1982

数据来源: Karger

ISSN:0030-2414    

DOI:10.1159/000225607

出版商:S. Karger AG    

年代:1982

数据来源: Karger

ISSN:0030-2414    

DOI:10.1159/000225608

出版商:S. Karger AG    

年代:1982

数据来源: Karger