摘要:

The oil perfused kidney preparation was used to determine the passive effects of increased venous and extrarenal pressure on renal vascular resistance. The dimensional tube factor of renal resistance varied inversely with the arteriovenous pressure gradient because this pressure difference also determined the pressure difference across the walls of the intrarenal vessels.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Chronic congestive heart failure was induced in dogs by the surgical production of tricuspid insufficiency and pulmonary stenosis. Glycerol-extracted trabecular bundles from the right and left ventricles of these dogs developed significantly less tension than did similar preparations from the hearts of normal dogs. The maximum working capacity of the bundles from failing hearts was lower than that of bundles from normal hearts, hut the rate of hydrolysis of adenosinetriphosphate was the same as that of normal heart preparations. Since glycerol-extracted muscle bundles retain the basic contractile properties of fresh, surviving whole muscle but are free from membrane, neurohormonal, ionic and pH effects and are isolated from energy-supplying systems of muscle, defective contractility and decreased working capacity of muscle bundles from failing hearts may be appropriately ascribed to physiochemical changes in the contractile protein, actomyosin. Such alterations are undoubtedly of structural significance, and are related to the conformation changes in actomyosin which characterize the contractile cycle of muscle.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The effects of diets high in carbohydrate or protein were studied on four dogs when normotensive and later when hypertensive. The results suggest that under certain conditions a cardiovascular homeostatic relationship may exist between diet, VEM-VDM and the sympathicoadrenal system.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID