ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Rapid alternating intrathoracic pressure changes caused by rapid breathing with partial obstruction to airflow caused a three to four fold increase in forearm blood flow whereas following the Valsalva maneuver the blood flow was decreased. Evidence is presented that these changes are brought about reflexly through alterations in vasoconstrictor tone. It is demontrated that the reflex changes are confined to skeletal muscle vessels, providing further evidence that the vasomotor centers controlling skin and muscle vessels can function independently.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The question as to whether unipolar precordial electrocardiographic leads provide clinical information not contained in a 3-lead orthogonal electrocardiogram remains unanswered. A simple, inexpensive switching-type resolver was designed for the investigation of this problem.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

A method is presented for the determination of the rates of movement of macromolecules into and out of specific tissues by analysis of the serum and tissue concentrations of the intravenously injected labeled macromolecule. Transfer rates of albumin into and out of rabbit aorta, skin, tendon, sclera, and cornea are given. These rates, and the steady-state ratios of tissue albumin to serum albumin, are interpreted in terms of current theory regarding the diffusion and filtration of albumin at capillary and lymphatic exchange sites in the tissues. Transfer rates for average body tissue, obtained by analysis of the serum concentration of intravenously injected labeled albumin, are compared with the transfer rates for the specific tissues studied.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The effect of antiarrhythmic drugs on the oxidation of glucose by heart tissue was studied. Quinine and quinidine inhibited oxygen consumption and glucose utilization by rat heart slices and homogenates, while chloroquine and procaine amide had little effect.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Addition of 0.1 per cent MER-13 to an atherogenic, high-cholesterol diet largely prevented the development of hypercholesteremia and aortic and coronary artery atheromatosis in cockerels. The hypocholesteremic effect was not obtained when MER-13 was administered following the removal of cholesterol from the diet. It is concluded that MER-13 inhibits absorption of cholesterol from the gastrointestinal tract.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The extent of triglyceride lipolysis by postheparin lipemia clearing factor (lipoprotein lipase) was studied in vitro in 8 atherosclerotic individuals. Varying doses of heparin were injected intravenously and subcutaneously and blood was drawn at stated time intervals for analysis. The rate of splitting of human low density lipoproteins was then determined by measurement of the rate of release of unesterified fatty acids upon incubation of postheparin plasma plus lipoproteins in vitro at 37 C. The data obtained gives a range of the minimum in vivo removal of alimentary neutral fat following an injection of heparin.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The diethanolamine salt of the mono (α,p-dimethylbenzyl) ester of d-camphoric acid (Gallogen) augmented diet-induced hypercholesterolemia and hyperlipemia in the rat, while depressing liver cholesterol and total lipid concentrations. Diethanolamine had virtually identical effects. Gallogen, given orally to rats with biliary fistulas had a slight hydrocholeretic effect, but did not influence biliary excretion of cholesterol, cholic acid, or chenodeoxycholic acid.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Innervated, nourished and ventilated dog lungs were perfused in situ with a technic which afforded adequate control of blood flow, pressures, pH and temperature. Variations of the pulmonary (hut not of the systemic) blood temperature was followed by pronounced changes of the pulmonary vascular resistance, believed to be attributable to pulmonary vasomotion.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Serotonin was the most potent pulmonary vasoconstrictor studied in an experimental preparation in which drugs injected into the pulmonary artery are temporarily excluded from the systemic circulation. Alterations in bronchomotor tone did not approach those produced by acetylcholine. Simultaneous systemic vascular or cardiac reflexes were not noted. Promethazine, LSD-25 and its 2-brom derivative were potent blockers of serotonin effects in the pulmonary circulation.

ISSN:0009-7330    

出版商:OVID    

年代:1958

数据来源: OVID