摘要:

Placental protein 4 (PP-4), a recently characterized glycoprotein from human placenta, was studied using a specific double-antibody radioimmunoassay in sera of 130 volunteers, 76 ovarian tumor patients and in ovarian tumor cyst fluid and ascites of 21 patients. Elevated levels ( > 3 μg/l) were found in 45 of 52 ovarian cancer patients (86.5%). PP-4 levels correlated significantly with staging. 31 patients with malignant ovarian tumor were monitored on 2–9 occasions during 5–82 weeks. Rising or falling levels of PP-4 correlated with progression or regression of disease in 25 of 31 instances (80.6%). Elevated levels were found in 10 of 24 benign and borderline ovarian tumors. Elevated PP-4 level does not indicate malignancy in each case. PP-4 can be regarded as tumor-associated antigen and a tumor marker in oncological practice.

ISSN:0378-7346    

DOI:10.1159/000293006

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

The main characteristic of malignant tumors is their capacity for local destructive spread as well as infiltration into the adjacent tissue. The present study was carried out to evaluate the hemodynamic alterations in patients with advanced cervix cancer. Data of 34 patients with cervix cancer are compared to 30 healthy women with normal history. The mean pulsatility index (PI) was significantly lower in cancer patients (PI = 1.75 ± 1.27) than in controls (PI = 3.18 ± 0.99). Use of noninvasive Doppler ultrasound study physiology of uterine hemodynamics in patients with cervix cancer is of great clinical relevance and paves the way for further investigations in screening programs for cervix cancer.

ISSN:0378-7346    

DOI:10.1159/000293007

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

Transrectal ultrasonographic examinations before surgery were performed on 27 patients with stage I endometrial cancer to assess myometrial invasion. The findings were compared with the histopathologic data obtained by surgery. Sensitivity and specificity of transrectal ultrasonography in myometrial invasion of endometrium cancer were 82.6 and 100%, respectively. Therefore, transrectal ultrasonography may be a useful diagnostic tool to determine the myometrial invasion, which is the most important prognostic factor in endometrial cancer.

ISSN:0378-7346    

DOI:10.1159/000293008

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

A second pregnancy was successfully achieved by a menopausal women who had previously conceived and delivered an infant using donated oocytes. The same nonanonymous oocyte donor provided the gametes for both procedures. Prior to embryo transfer, the functionally agonadal recipient received exogenous steroid hormone replacement therapy. Both pregnancies followed the transfer of 5 embryos which were conceived by the in vitro fertilization of the donated oocytes with the recipient husband’s sperm. The first pregnancy ended with an intra-uterine fetal demise at 40 weeks gestation. The second pregnancy is proceeding unremarkably.

ISSN:0378-7346    

DOI:10.1159/000293009

出版商:S. Karger AG    

年代:1991

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000293010

出版商:S. Karger AG    

年代:1991

数据来源: Karger

摘要:

The authors report a case of nutritional zinc deficiency in a young (18-year-old) Turkish woman, who previously delivered 2 anencephalic stillborn infants. The patient was supplemented with 22.5 mg oral zinc sulfate (100 mg ZnSO4 7H2O) for 5 months after her second delivery prior to her third pregnancy. Her blood (plasma and red blood cell) and hair zinc levels returned to normal following zinc supplementation. Good response to Zn supplementation was another criterion of Zn deficiency in this particular case. After an uneventful gestational period, she delivered an apparently normal full-term male child who has grown normally during the first 12 months.

ISSN:0378-7346    

DOI:10.1159/000293011

出版商:S. Karger AG    

年代:1991

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000289250

出版商:S. Karger AG    

年代:1910

数据来源: Karger

摘要:

We treated a patient with primary vaginal carcinoma. Very valuable preoperative diagnostic imaging of the carcinoma obtained by transvaginal color Doppler and magnetic resonance is reported herein.

ISSN:0378-7346    

DOI:10.1159/000293012

出版商:S. Karger AG    

年代:1991

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000289251

出版商:S. Karger AG    

年代:1910

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000289252

出版商:S. Karger AG    

年代:1910

数据来源: Karger