摘要:

The objective of this retrospective study was to evaluate the usefulness of abdominal and vaginal sonohysterography (SHG; considered both singly and in combination) for the diagnosis of uterine polyps. Fifty fertile women hospitalized for hysterectomy for benign gynecologic indications were enrolled. Main outcome measures were preoperative conventional vaginosonography, transabdominal and vaginal SHG, hysteroscopy and histologic evaluation of the surgical specimen. Conventional vaginosonography had a sensitivity of 33.3% and a specificity of 100%; the predictive values of abnormal and normal scans were 100 and 79.5%, respectively. Transabdominal SHG had a sensitivity of 75% and a specificity of 100%. The predictive value of an abnormal scan was 100%; that of a normal scan 91.2%. Vaginal SHG had a sensitivity of 58.3% and a specificity of 100%; the predictive value of an abnormal scan was 100%, that of a normal scan 86.1 %. The combination of the two kinds of SHG had a sensitivity of 91.7% and specificity of 100%; the predictive value of an abnormal test was 100% and that of a normal test 96.9%. The sensitivity, specificity and predictive values of abnormal and normal hysteroscopic examination were all 100%. In conclusion, the presence of endouterine polyps can be effectively investigated by SHG; nevertheless, hysteroscopy is more sensitive, being capable of detecting even very small endouterine neoformations.

ISSN:0378-7346    

DOI:10.1159/000292494

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

In this prospective study, we compared the histological results of Pipelle endometrial sampling (PES) with that of hysterectomy to examine whether endometrial sampling with the Pipelle device can accurately diagnose endometrial carcinoma. PES was performed in 26 patients with known endometrial carcinoma whose initial therapy consisted of hysterectomy. Discomfort and pain during the biopsy were reported to be mild by 22 patients, moderate by 3 patients and severe by only 1 patient. All of the samples were found to be adequate. Twenty-four of 26 PES confirmed endometrial carcinoma, a correlation of 95%, and the histological grade reported on PES agreed with that of hysterectomy specimens in 87.5% of the patients. On the other hand, the tumor grade in the specimens obtained at dilation and curettage correlated with hysterectomy specimens in 95% of the patients. We conclude that Pipelle is an accurate device in patients with endometrial carcinoma.

ISSN:0378-7346    

DOI:10.1159/000292495

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

The presence of human papillomavirus (HPV) type 16 and 18 transcripts was determined by reverse transcription/polymerase chain reaction (PCR) in ovarian and endometrial carcinoma tissue. HPV-16 DNA sequences were detected in 50.0% (9/18) of the ovarian carcinomas and in 44.4% (8/18) of endometrial carcinomas. HPV-18 DNA sequences were found in 16.7% (3/18) of both the ovarian and endometrial carcinomas. Using RNA-PCR analysis, we found 3 out of 9 (33.3%) of the HPV-16 DNA-positive and 1 in 3 (33.3%) of the HPV-18 DNA-positive ovarian carcinomas were transcriptionally active, contrary to the HPV-16 DNA-positive or HPV-18 DNA-positive endometrial carcinomas. The results suggest that HPV RNA may be detected in ovarian carcinomas though its biological significance remains to be elucidated. HPV RNA is not demonstrable in endometrial carcinoma using the current primer sets. Further investigations are necessary for a final conclusion.

ISSN:0378-7346    

DOI:10.1159/000292496

出版商:S. Karger AG    

年代:1994

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000292497

出版商:S. Karger AG    

年代:1994

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000292499

出版商:S. Karger AG    

年代:1994

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000290898

出版商:S. Karger AG    

年代:1913

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000290899

出版商:S. Karger AG    

年代:1913

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000290900

出版商:S. Karger AG    

年代:1913

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000290901

出版商:S. Karger AG    

年代:1913

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000290902

出版商:S. Karger AG    

年代:1913

数据来源: Karger