摘要:

Serum concentrations of androstenedione, testosterone and dehydroepiandrosterone sulfate (DHEAS) were measured in 29 patients with premature ovarian failure (POF) and an identical number of age-matched normal control subjects. The study was aimed at determining possible differences in androgen concentrations of ovarian and adrenal origin in POF patients and age-matched normal menstruating controls. Serum testosterone and DHEAS concentrations in the 2 populations were not significantly different. The serum androstenedione concentration in the POF patient group (3,077.50 ± 1,122.33 pmol/l) was significantly lower than in age-matched normal control subjects (4,167.70 ± 1,381.09 pmol/l, p < 0.005), possibly reflecting the loss of ovarian androstenedione secretion and/or a subtle defect in adrenal steroidogenic capacity.

ISSN:0378-7346    

DOI:10.1159/000291817

出版商:S. Karger AG    

年代:1997

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000292206

出版商:S. Karger AG    

年代:1916

数据来源: Karger

摘要:

Objectives: To investigate the signs, symptoms and changes in the vaginal milieu that could be associated with cervical human papillomavirus infection (CHPI). Study design: Women (n = 972) attending for contraceptive advice were tested for human papillomavirus in cervical samples. Results of gynecological history, examination, and vaginal wet smear findings were compared between CHPI patients and negative women. Results: Sixty-six (6.8%) of the women had a CHPI. Bacterial vaginosis was more common among those with, than without, CHPI, but the significance of this association was abolished after adjustment for age and for markers of sexual risk-taking. Vaginal discharge with a fishy odor, a positive amine test, and genital fissures showed significant correlations with CHPI, which persisted after adjustments. Symptoms of proctitis also correlated with CHPI, and remained significant after adjustment for anal sex. Conclusion: Bacterial vaginosis is associated with the presence of CHPI, possibly due to sexual behavioral factors. However, several other features, in particular the presence of amines, may be independently associated with CHPI.

ISSN:0378-7346    

DOI:10.1159/000291818

出版商:S. Karger AG    

年代:1997

数据来源: Karger

摘要:

This was a retrospective study analyzing the need for reoperation for recurrent endometriomas after surgical therapy. There were 104 women who were followed after surgical excision of endometriomas, with a cross section of 46 gynecologic surgeons. When using a life-table for follow-up analysis, only 2.9% of all patients had reoperation for recurrence, with a maximum recurrence probability of 7% at 32 months of follow-up.

ISSN:0378-7346    

DOI:10.1159/000291819

出版商:S. Karger AG    

年代:1997

数据来源: Karger

摘要:

This study aimed at testing the hypothesis that lower uterine arterial (UA) Doppler indices are caused by increased uterine volume rather than the presence of myoma. Uterine volumes were calculated and uterine and/or myomal arterial pulsatility index (PI) and resistance index (RI) were obtained by transvaginal color Doppler ultrasonography. The mean uterine volume in the myomatous group (276.2 cm3; range 65–928 cm3, n = 100) was significantly greater than that of the control group (101.4 cm3; range 36–171 cm3; n = 60; p = 0.00). The mean UA PI and RI values in the study group were significantly lower than their corresponding values in the control group (0.77 ± 0.08 and 1.69 ± 0.47 vs. 0.82 ± 0.06 and 1.97 ± 0.49, respectively, p = 0.01). When the myomatous uterine volumes of the study group were categorized into two subgroups (<200 and ≧200 cm2) the UA PI and RI values were lower in the latter group (p = 0.006 and p = 0.015, respectively). However, after analysis of receiver-operator-characteristic curves, none of the UA Doppler indices could differentiate the myomatous uterus from the norm

ISSN:0378-7346    

DOI:10.1159/000291820

出版商:S. Karger AG    

年代:1997

数据来源: Karger

摘要:

In an attempt to assess the hypothesis that different endometrial sites may respond differently to tamoxifen exposure in postmenopausal women, hysteroscopic selected endometrial histology was investigated in 175 postmenopausal breast cancer patients who received continuous treatment with tamoxifen, and in 27 similar patients not treated with tamoxifen who served as controls. In the tamoxifen-treated patients 14 (8.0%) developed endometrial polyps. Of 14 patients, 8 (57.2%) each displayed atrophic endometrium in the same histologic specimen, 5 (35.7%) each had coexisting simple hyperplasia, and 1 (7.1%) other had complex hyperplasia. Another 21 (12.0%) developed simple or complex hyperplasia. The endometrial hyperplasia coexisted with atrophic endometrium in all these patients. All these lesions were selectively identified by hysteroscopic examination prior to the endometrial biopsy. In the control group 3 (11.0%) had simple hyperplasia and 2 (7.4%) had endometrial polyps. The above results support the hypothesis that the endometrium of postmenopausal breast cancer patients on tamoxifen treatment may possess different responses to tamoxifen exposure.

ISSN:0378-7346    

DOI:10.1159/000291821

出版商:S. Karger AG    

年代:1997

数据来源: Karger

摘要:

Venous pulsatile flows were detected by pulsed Doppler flow velocimetry throughout the entire umbilical cord in 2 cases of intrauterine growth retardation. Although the hearts of these fetuses had no anomalies and their inferior vena cava flows had normal flow velocity patterns, their cords were severely coiled. In these cases, the pulsatile flow in the umbilical cord vein was caused not by an increase in the preload of the fetal heart, but only by hypercoiling of the umbilical cord. This phenomenon also suggests that the coiled umbilical cord exerts a pump-like effect known as a ‘pulsometer’.

ISSN:0378-7346    

DOI:10.1159/000291822

出版商:S. Karger AG    

年代:1997

数据来源: Karger

摘要:

Malignant struma ovarii is a rare form of ovarian carcinoma; only 3 cases of its pure papillary type have been reported in the literature. A new case of malignant papillary struma ovarii arising in an asymptomatic 32-year-old woman is presented. Due to its rarity, there has been confusion in the diagnosis and management of malignant struma ovarii. Criteria for the diagnosis of malignant papillary struma ovarii are proposed. Conservative treatment after a complete staging procedure is possible due to the usually benign course and low incidence of metastases of this tumor.

ISSN:0378-7346    

DOI:10.1159/000291823

出版商:S. Karger AG    

年代:1997

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000292207

出版商:S. Karger AG    

年代:1916

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000292208

出版商:S. Karger AG    

年代:1916

数据来源: Karger