摘要:

2 Cases of mixed mesodermal tumor of the ovary with elevated peripheral levels of alpha-fetoprotein (α-FP) were studied. The morphology of these tumors is presented. The finding of hyaline droplets of α-FP is of special interest. The histogenesis of the tumor was reappraised in light of the increased level of the marker.

ISSN:0378-7346    

DOI:10.1159/000299143

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Three types of packages containing enough sanitary supplies for one menstrual period were weighed and distributed to 100 subjects to determine adequacy of supplies and compliance to protocol. Returned packages were then reweighed to determine total menstrual loss. No subject used all the supplies in her package; therefore, packages contents were deemed ample. 7 subjects added their own purchased products to their packages; since added products were specified by name, weight corrections were easily made. 2 subjects lost unused supplies which were specified, and weight corrections were made accordingly. Evaporative loss from sealed and stored and frequently opened packages was measured. 100 g distilled water were added to contents inside 60 packages which were sealed and set aside 7 days. Average loss from these packages was 0.65 ± 0.57 g. 5 g water were added to 60 packages 4 times daily for 5 days (100 g total). Then packages were set aside for 2 days and weighed on day 7. Average loss from these packages was 1.25 ± 0.85 g. The combination of storage plus frequent opening resulted in an average loss of 1.90 ± 0.87 g. Thus, the direct-weight method permits recovery of 97–98% of sample.

ISSN:0378-7346    

DOI:10.1159/000299144

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

The effects of nicotine consumption on uteroplacental blood flow were studied in 20 pregnant women by means of placental blood flow measurements using indium-113m-transferrin. Smokers were found to have a higher rate of poor perfusion patterns than subjects of a control group. In addition, the number of cigarettes smoked daily was significantly correlated with the placental perfusion type. The mean birth weight of infants born by smokers was 250 g lower than in the control group. The results suggest that smoking during pregnancy may compromise uteroplacental blood flow and thus result in poor fetal development.

ISSN:0378-7346    

DOI:10.1159/000299145

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

The relationship of maternal weight status to the probability of appearance of one or a combination of three or more undesirable pregnancy events (UPE) was analyzed. A total of 711 women presenting for prenatal care before 16 weeks estimated gestational age were categorized according to early pregnancy body mass (EPBM) and subsequent weight gain. Statistical analysis revealed weight gain related to the appearance of one UPE only in women with an EPBM less than 120 pounds. In gestations complicated by three or more UPEs, a relationship to weight gain was shown only in women with an EPBM of 120–199 pounds.

ISSN:0378-7346    

DOI:10.1159/000299146

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Breast engorgement and galactorrhea were observed in many patients receiving ritodrine treatment to delay labor due to premature contractions. In an attempt to understand the causes for these phenomena, serum prolactin, progesterone, estradiol and estriol excretion were measured in 11 women. No statistical difference was found in these parameters after ritodrine administration. It can thus be assumed that breast engorgement and galactorrhea after ritodrine treatment are unrelated to changes in these hormones but might be mediated by some other factors or probably by the premature contractions themselves.

ISSN:0378-7346    

DOI:10.1159/000299147

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Maternal and cord blood samples were collected in 60 cases with or without rupture of membranes before and at term. Serum concentrations of calcium, copper, iron and zinc were determined by proton-induced X-ray emission. Maternal and cord serum cerulo-plasmin and maternal hemoglobin were also determined. Mothers with preterm delivery showed significantly lower hemoglobin values than those with delivery at term. Concentrations of calcium, iron and zinc were higher in cord than in maternal serum whereas maternal copper levels were higher than respective cord levels in all groups. The cord copper and ceruloplasmin and also their fetal/maternal ratios were significantly lower in the group with preterm premature rupture of fetal membranes (PROM) than in other groups. Maternal serum zinc and calcium were lower in preterm groups than in term groups. The study suggests a possible role of copper in preterm PROM and of zinc in the initiation of preterm labor, whereas calcium and iron do not seem to be involved in the etiology of prematurity or PROM.

ISSN:0378-7346    

DOI:10.1159/000299148

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Changes in the peripheral blood leucocyte count, lymphocyte subpopulations, and in ‘in vitro’ responses of lymphocytes to phytohaemagglutinin and tuberculin after induced labour were investigated in 10 normal parturients and their newborns. Every other parturient was given segmental epidural analgesia at level T10–12 for pain relief during the first stage of labour. The remaining mothers served as controls. The results of blood samples taken from the mothers before induction of labour and from the newborns immediately after delivery served as basal values against which the results of samples drawn on the 1st and on the 5th day following delivery were compared. A significant (p < 0.05) increase from the basal values in the total leucocyte count after delivery was found only in those mothers not given epidural analgesia and in their newborns. Similarly, a significant (p < 0.01) decrease in the T cell count characterized by both E rosette formation and acid alpha-naphthyl acetate esterase staining was found in the peripheral blood only in the mothers (but not the newborns) without epidural analgesia. The differences between the research groups were not, however, significant. The lymphocyte response to phytohaemagglutinin on the 1st and on the 5th day after delivery was also significantly (p < 0.05) lower in the newborns of the mothers not given epidural analgesia than in those of the mothers given it. The present results show that the depression induced by the stress of parturition in some parameters of cell-mediated immunity of mothers and newborns can be at least partly prevented by using segmental epidural analgesia.

ISSN:0378-7346    

DOI:10.1159/000299149

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

We evaluated the anti-HBs titers in 20 babies born to HBsAg-positive mothers and receiving different programs designed to prevent hepatitis B. Passive prophylaxis by HBIG for 6 months assured detectable antibody levels in the same period. 3 months after the last injection we could detect antibodies in 5 out of 9 cases. In no case could we detect antibodies 6 months after the last dose. Active prophylaxis by hepatitis B vaccine was able to raise anti-HBs response in 8 out of 12 babies after two or three very small doses (1.25 μg of antigen). 2 of these babies were given the first dose at birth. Small doses of vaccine were immunogenic in the presence of passive antibodies.

ISSN:0378-7346    

DOI:10.1159/000299150

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

There is already sufficient evidence in the literature that alcohol abuse during pregnancy has a toxic effect upon the developing fetus; however, previous studies have not revealed any morphological changes in fetal or newborn liver specimens from animals exposed to alcohol in utero. As it is known that alcohol freely crosses the placental barrier, this investigation was an attempt to demonstrate that structural abnormalities can indeed be identified in neonatal mouse liver specimens from pups exposed to alcohol in utero. Chosen as a model for this study was the C57BL/KsJ mouse strain as this particular animal demonstrates an alcohol preference paralleling that of the human alcoholic. Findings appear to indicate the presence of abnormal changes on the morphological level in these study animals.

ISSN:0378-7346    

DOI:10.1159/000299151

出版商:S. Karger AG    

年代:1984

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299152

出版商:S. Karger AG    

年代:1984

数据来源: Karger