ISSN:0378-7346    

DOI:10.1159/000283486

出版商:S. Karger AG    

年代:1902

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283487

出版商:S. Karger AG    

年代:1902

数据来源: Karger

摘要:

Serum concentrations of PP5 were measured by radioimmunoassay in 219 women with normal pregnancies and 163 women whose pregnancies were complicated. PP5 in serum disappeared rapidly after delivery, with a half-life of 5–10 min in the first 10min. Serum PP5 levels were higher in uterine than in antecubital venous blood. In normal pregnancies, PP5 was detectable at 7–8 weeks of gestation; its mean concentration rose gradually to a maximum of 17.8 ± 10.2 ng/ml at 34–35 weeks of gestation. Elevated serum PP5 concentrations were noted in patients whose pregnancies were complicated by toxemia of pregnancy with appropriate-for-date baby or by twin pregnancy. Low serum PP5 concentrations tended to be found in patients whose pregnancies were complicated by abortion, intrauterine fetal death, and hydatidiform mole. Marked abnormal PP5 levels were not found in patients with maternal diabetes and placenta previa. These findings suggest that the assay of serum PP5 concentrations can be a useful parameter in determining the prognosis of abnormal pregnancies.

ISSN:0378-7346    

DOI:10.1159/000299207

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283488

出版商:S. Karger AG    

年代:1902

数据来源: Karger

摘要:

We have examined whether there are changes in the day-night variation in plasma cortisol in normal women during the third trimester of pregnancy. Maximum cortisol values at 07.30–10.30 h were similar at 30–31, 34–35 and 38–39 weeks of pregnancy. The daily increment in plasma cortisol (fold change) was greater, and the trough values lower at 30–31 than at 38–39 weeks. The time taken for plasma cortisol to fall to 50% of the morning maximum values was longer at 38–39 weeks than at 30–31 weeks of pregnancy. These changes in cortisol rhythms may have implications with respect to alterations in circadian patterns of maternal steroid concentrations as well as fetal biophysical functions.

ISSN:0378-7346    

DOI:10.1159/000299209

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283489

出版商:S. Karger AG    

年代:1902

数据来源: Karger

摘要:

To determine the relation of diurnal changes in plasma progesterone to those in cortisol and estriol we measured the concentrations of progesterone, cortisol and estriol in samples of plasma taken at 30- to 60-min intervals throughout 24 h from women at 30–31, 34–35, and 38–39 weeks of gestation. Plasma progesterone showed a significant diurnal rhythm at 30–31 and at 34–35 weeks of pregnancy, with troughs at 04.30–10.00 h. Major peaks occurred between 15.30 and 02.30 h. There was no diurnal rhythm in progesterone at 38–39 weeks. Plasma progesterone showed a significant negative correlation with plasma cortisol at 30–31 and 34–35 but not at 38–39 weeks. Plasma progesterone showed a significant positive correlation with estriol at 34–35 and at 38–39 weeks. We suggest that daily fluctuations in plasma progesterone may be related to the concentration of plasma cortisol, either directly by competition for binding sites on transcortin, or indirectly after modulation of fetal pituitary-adrenal function by maternally derived glucocorticoid.

ISSN:0378-7346    

DOI:10.1159/000299211

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283490

出版商:S. Karger AG    

年代:1902

数据来源: Karger

摘要:

Mesh of absorbable polyglactin 910 instead of human tissues or nonabsorbable synthetic materials was utilized for retropubic sling procedures in 21 women with urinary stress incontinence. The patients have been observed for a period ranging from 4 to 14 months. 20 of them are continent while there was 1 relapse after 2 months. The postoperative complications were minimal, and there has been no instance of foreign body reaction.

ISSN:0378-7346    

DOI:10.1159/000299212

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

Nonesterified fatty acids (NEFA) from C12 to C24 have been determined in sera of 13 young women at menstruation, and in the follicular and luteal phase of the menstrual cycle applying a new gas chromatographic microliter method. Neither the total NEFA content nor the concentrations of individual fatty acids showed significant differences in the three phases of the menstrual cycle. With the exception of stearic acid we found almost constant relative concentration values for the individual fatty acids within the medium range of the long-chain NEFA spectrum. Intraindividual andinterindividual dispersion was hardly greater than the variation caused by the method of determination itself, whereas the intra- and interindividual scattering of the rim fractions of the NEFA spectrum was much more distinct. The coefficients of variation for the total as well as individual NEFA content related to all examined women at any phase of the menstrual cycle were lower than 40 % with the exception of the rare erucic acid, behenic acid and lignoceric acid.

ISSN:0378-7346    

DOI:10.1159/000299215

出版商:S. Karger AG    

年代:1983

数据来源: Karger