摘要:

25 singleton pregnancies were terminated by cesarean section between 28 and 33 weeks of gestation because of suspected growth retardation and abnormal unstressed cardiotocograms. Only infants with birth weights below the tenth centile were considered. 17 survived and were neurologically examined at 2.5–7 years of age. 2 were neurologically abnormal (1 had an adrenogenital syndrome) and 1 showed minor neurological dysfunction. Cesarean section appears acceptable in the management of intrauterine growth retardation with fetal distress in the early third trimester.

ISSN:0378-7346    

DOI:10.1159/000299030

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Although nausea and vomiting in early pregnancy is extremely common, very little information on the cause and course of this disorder is available in the literature. A prospective laboratory and clinical study of 102 consecutive healthy pregnant women was undertaken to evaluate nausea and vomiting in relation to clinical data, serum electrolytes, creatinine, total protein and hemoglobin. Multigravidae suffered from emesis gravidarum at a higher rate than did primigravidae. The frequency of emesis was especially high in women with short intergestational intervals. During pregnancy there was a decline in systolic blood pressure only in non-emetic women. The diastolic blood pressure in late pregnancy was significantly higher in emetic women than in non-emetic subjects. All laboratory values were within normal ranges. However, major changes occurred during pregnancy but some alterations were noted only in the emetic pregnancy. A different response to the hormonal situation is suggested to explain the dissimilarities between the emetic and non-emetic pregnancy.

ISSN:0378-7346    

DOI:10.1159/000299031

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

We studied the effects of caffeine ingestion during pregnancy. A total number of 9,921 healthy pregnant women with a gestational age after 24 weeks were subjected to the study. The women who drank more than 5 cups of coffee per day had a high incidence of impending abortion, premature labor, and fetuses small for gestational age. The heavy coffee drinkers among the pregnant women had high rates of spontaneous abortion, chromosomal abnormality and congenital multi-anomalies. However, we would like to stress that the multiple socioeconomic variables might be more important than any direct effect of caffeine.

ISSN:0378-7346    

DOI:10.1159/000299032

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

High concentrations of arginine vasopressin (AVP) in arterial umbilical cord blood at the time of delivery have been attributed to either a generalized increase in the activity of the fetal endocrine system at the onset of labor or to fetal asphyxia. We measured AVP in amniotic fluid, arterial and venous cord blood and in maternal venous blood from 13 patients at 38–40 weeks of gestation at the time of elective cesarean section with a nonasphyxic fetus (group I), in amniotic fluid from 19 patients at 15–17 weeks of gestation (group II) and in venous blood from 13 nonpregnant control subjects (group III). Our results showed a high concentration of AVP in the amniotic fluid both in the middle and at the end of normal pregnancy and at the same level as in arterial cord blood, whereas AVP in the venous cord blood was significantly lower and at the same level as in the maternal venous blood and in the control group. It is concluded that the fetus produces AVP and this is at least not solely caused by fetal asphyxia or related to parturition.

ISSN:0378-7346    

DOI:10.1159/000299033

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The authors have evaluated placental blood flow using a non-invasive radioisotopic approach. The procedure involves the intravenous administration of 113mIn and the technique is a modified version of a previously reported method for a non-diffusive tracer kinetics analysis. The method is presented in detail and its performance is evaluated in 17 normal and 32 pathologic pregnancies (19 intrauterine growth retarded patients; 7 patients with iso-Rh immunization; 5 patients with gestational diabetes, and 1 pregnancy with extensive fetal malformation which was not included in any group). The normal pregnancies showed a flow index of 5.34 ± 1.64 (1 SD) units compared to the pathological pregnancies value of 2.73 ± 0.73 (1 SD) units (p < 0.001). The conclusions drawn are: (1) the method is very well suited to clinical evaluation of placental blood flow; (2) the evaluation of placental blood flow cannot be directly equated with fetal development as it is not its only determinant, and (3) no other independent test to evaluate the radioisotopic study in terms of accuracy exists.

ISSN:0378-7346    

DOI:10.1159/000299034

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

8 post-menopausal, post-oophrectomy and hysterectomy women had a 100-mg pure 17β-estradiol pellet installed in their subcutaneous abdominal tissue. The pellet caused a marked systemic hormonal effect in these patients causing an up to 30-fold increase in plasma estradiol and a marked decrease in follicle-stimulating hormone levels. It showed a significant increase in plasma high density lipoprotein (HDL) and HDL to total cholesterol ratio levels, no change in plasma triglycerides and very low density lipoprotein levels and some decrease in total cholesterol and low density lipoprotein cholesterol concentrations. These results differ from the previously reported influence of synthetic hormonal preparations on the same plasma lipids and lipoproteins.

ISSN:0378-7346    

DOI:10.1159/000299035

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The effectiveness of ultrasound in the follow-up of tumor masses during chemotherapy was investigated over a period of 3 years in 74 patients with proven ovarian cancer. 47 had stage 3 disease, and 22 showed recurrence. Two or more examinations were performed in 65% of the patient. A correlation with surgical second look showed a correct diagnosis in 67.6%. The results of ultrasonographic follow-up when compared with clinical monitoring showed 75% concordant judgments on the therapeutical tumor response. The validity and limitations of this technique are discussed.

ISSN:0378-7346    

DOI:10.1159/000299036

出版商:S. Karger AG    

年代:1985

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299037

出版商:S. Karger AG    

年代:1985

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299038

出版商:S. Karger AG    

年代:1985

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000284302

出版商:S. Karger AG    

年代:1904

数据来源: Karger