ISSN:0378-7346    

DOI:10.1159/000291987

出版商:S. Karger AG    

年代:1915

数据来源: Karger

摘要:

Objective: To study differences in maternal weight and weight gain for 48 twin-pregnant women with at least one stillbirth, versus 96 control mothers where both twin pairs survived the perinatal period. Material and Methods: In all, 48 twin gestations with one or both twins dead before or during birth (cases), in a defined region with 12 hospitals in southern Sweden between 1973 and 1989, were identified by using information stored at the Medical Birth Registry, the National Board of Health and Welfare, Stockholm. For each case pregnancy, two control twin pregnancies were selected; matching criteria were same parity and delivery unit, and similar year of delivery ( ± 1 year) and maternal age ( ± 5 years). Results: Case and control women had a similar number of maternal body weight measurements during pregnancy, 8.9 vs. 8.0 (t = 1.5, p > 0.05). No significant difference between cases and controls was found regarding maternal weight (x ± SEM) at 12 weeks of gestation (68.0 ± 1.4 vs. 68.1 ± 0.9 kg; t = 0.2, p > 0.05), or in weight gain/pregnancy week (0.59 ± 0.28 vs. 0.61 ± 0.19 kg; t = 0.8; p > 0.05). Conclusion: The results of this study indicate that repeated body weight measurements of the twin-pregnant woman are of very limited value in the identification of a twin-pregnant woman later to face stillbirth.

ISSN:0378-7346    

DOI:10.1159/000291879

出版商:S. Karger AG    

年代:1996

数据来源: Karger

摘要:

This study deals with the effects of smoking on serum ceruloplasmin and its ferroxidase activity in pregnant women. The mean value ( ± SD) of serum ceruloplasmin in women smokers during pregnancy is significantly higher (p < 0.01) in comparison to that of nonsmokers, whereas the ferroxidase activity of ceruloplasmin in smokers is not significantly different from that of nonsmokers. These findings suggest that ceruloplasmin in women smokers loses part of its ferroxidase activity.

ISSN:0378-7346    

DOI:10.1159/000291880

出版商:S. Karger AG    

年代:1996

数据来源: Karger

摘要:

To investigate the impact of insulin secretion on pregnancy outcome, we studied 102 patients at risk for glucose intolerance between 28 and 34 weeks of gestation. All patients had a 3-hour oral glucose tolerance test (OGTT, 100 g glucose), and glucose and insulin plasma levels were assayed: 32 patients had a gestational diabetes (GDM); 25 had an impaired gestational glycemic tolerance (IGGT), and 45 with normal OGTT constituted the control group. No significant difference between groups was seen for pregnancy outcome. Based on the mean ± 2 SD of insulin secretion of the control group, IGGT/GDM patients were classified as normoinsulinemic (34 patients), hyperinsulinemic (17 patients), or hypoinsulinemic (6 patients). The hyperinsulinemic IGGT/ GDM group showed a greater incidence of pregnancy-induced hypertension (p < 0.03), while the percentile birth weight was significantly lower (p < 0.01) with respect to normo-hypoinsulinemic patients. Moreover a higher glucose/ insulin ratio was significantly related to birth weight (p < 0.01). Our results suggest an impact of insulin secretion on pregnancy outcome and support the importance of determining the insulinemic pattern in pregnant patients at risk for glucose intolerance

ISSN:0378-7346    

DOI:10.1159/000291881

出版商:S. Karger AG    

年代:1996

数据来源: Karger

摘要:

Objective: To evaluate the effect of labor pains or fetal distress on concentrations of interleukin-1 receptor antagonist (IL-1ra) in cord blood. Methods: Umbilical cord interleukin-1 β (IL-1β) and IL-1 ra were measured in 24 normal appropriately grown newborns delivered vaginally (VD group), 10 normal appropriately grown newborns delivered by elective cesarean section (ECS group), and 5 appropriately grown newborns with fetal distress (FD group). Umbilical cord arterial blood pH and PO2 were also measured. Results: Umbilical artery blood pH and PO2 in the VD group were not significantly different from those in the ECS group. Umbilical artery blood pH and PO2 in the FD group were significantly lower than those in the VD group (p < 0.05). Umbilical artery blood pH in the FD group was significantly lower than that in the ECS group (p < 0.05), but no significant difference for umbilical artery blood PO2 was found between the FD and ECS groups. IL-1β levels were undetectable in the three groups of neonates. There were no significant differences for concentrations of IL-1ra in cord blood among the groups. Conclusion: These results suggest that the labor pain or fetal distress does not affect concentrations of IL-1ra in cord blood.

ISSN:0378-7346    

DOI:10.1159/000291882

出版商:S. Karger AG    

年代:1996

数据来源: Karger

摘要:

Randomly selected parturients with term singleton pregnancies from two different settings, 83 from Mozambique and 90 from Sweden, entered the study. All of them underwent elective cesarean section, which enabled sterile harvesting of amniotic fluid (AF). AF samples were then tested for antibacterial activity (ABA). Background data and nutritional status were compared. Average age was 32.7 and 30.7 years (n.s.), average parity 6.6 and 1.6 (p < 0.0001), average number of antenatal visits 4.9 and 11.6 (p < 0.0001), and average birthweight 3,194 and 3,688 g (p < 0.01), respectively. Body mass index, mid-upper-arm circumference and hemoglobin did not show any significant differences. The average ABA of AF was more than 50% higher in Swedish than in Mozambican specimens (p < 0.0001). Less than one-sixth of Mozambican women reached the average ABA of AF from Swedish women. Bacterial outgrowth delay equal to or above 3 h was encountered in 13% of Mozambican AF as against 61% of Swedish AF (OR 0.10; 95% CI 0.05–0.19). Histopatho-logical examinations of the placenta, nonplacental membranes and umbilical cord showed inflammatory lesions in 29% of the Mozambican parturients and in 13% of Swedish parurients (OR 2.65; 95% 1.00–6.98). It is probable that the lower antibacterial activity in Mozambican AFs reflects an increased vulnerability to ascending genital infections during late pregnancy.

ISSN:0378-7346    

DOI:10.1159/000291883

出版商:S. Karger AG    

年代:1996

数据来源: Karger

摘要:

A luteal phase defect (LPD) is a clinical problem leading to infertility and is characterized by reduced progesterone levels during the luteal phase. Serum lipoperoxidation is an expression of cellular hypoxic damage occurring under all stress-oxidative conditions. Forty-eight consecutive infertility patients, according to the infertility class II of the WHO classification, underwent clinical observation. Twenty-five patients ovulated constantly with a normal luteal phase, while the other 23 had a LPD, hormonally and histologically assessed. The luteal phase was monitored biochemically by titration of progesterone, oestradiol, and serum lipid peroxides during the ovulatory period and 6–12 days after ovulation. The mean plasmatic concentration of oestradiol was not statistically different between the LPD and the normal-cycle groups, while a statistically significant difference was found for progesterone plasmatic concentrations between the LPD and the normal-cycle groups (p < 0.05); a greater statistical difference was also found in the mean serum lipoperoxide titration (p < 0.001). These findings suggest that serum lipoperoxidation titration may be a useful tool in the study of the interactions between hormonal milieu and sympathetic activity.

ISSN:0378-7346    

DOI:10.1159/000291884

出版商:S. Karger AG    

年代:1996

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000291988

出版商:S. Karger AG    

年代:1915

数据来源: Karger

摘要:

In the current study, the uterine fluid level of human decidua-associated protein (hDP) 200 was measured in 80 women with abnormal uterine bleeding and normal histology. In 20 women the level of hDP200 was also correlated with the endometrial thickness measured by transvaginal ultrasonography. The results demonstrated the same distribution and similar levels of uterine fluid hDP200 throughout the menstrual cycle as in regularly cycling women, with no correlation between the levels of hDP200 and the endometrial thickness. Thus, the test for uterine fluid hDP200 could serve to discriminate between benign and pathological examinations of endometrial biopsies in women of reproductive age, women with abnormal uterine bleeding and benign conditions of the endometrium. Very low levels of hDP200 are indicative of endometrial hyperplasia or carcinoma.

ISSN:0378-7346    

DOI:10.1159/000291885

出版商:S. Karger AG    

年代:1996

数据来源: Karger

摘要:

Our purpose was to assess the correlation between the estimated volume based on ultrasonic measurement in vivo and the actual weight of the diseased uterus after hysterectomy, and then retrospectively tried to establish a simple equation to convert the volume into the weight in grams. A total of 105 women with nonmalignant diseased uteri which were prepared to undergo laparoscopy-assisted vaginal hysterectomy had had preoperative ultrasound scanning to estimate the uterine size by measuring three dimensions including the length (L), width (W) and anteroposterior (AP) diameter. The uterine volume was calculated by the use of a prolate ellipsoid formula (4/3 × π × L/2 × W/2 × AP/2). Actual uterine weight was immediately taken after extirpation of the uterus. Linear regression analysis revealed uterine weight (g) = 50.0 + 0.71 × volume (cm3), with correlation coefficient = 0.93 and SE = 49.6 g. There was a close, positive correlation between the estimated uterine volume and actual uterine weight. With utilization of this equation, the uterine size in vivo can thus be expressed as a concrete, objective value in weight instead of ‘weeks’ size’ by comparison with pregnant uterus, which has been commonly used in traditional gynecologic practice.

ISSN:0378-7346    

DOI:10.1159/000291886

出版商:S. Karger AG    

年代:1996

数据来源: Karger