摘要:

Reproductive function following advanced ovulation induced by a single injection of 1 μg synthetic luteinizing hormone-releasing hormone (LH-RH) has been studied in rats. While advanced ovulation induced by an injection of the agent on the day of proestrus was followed by pregnancies occurring as frequently as those in spontaneous ovulation group, incidences of mating behavior, fertilization, and pregnancy were considerably reduced in the advanced ovulation group when induced by an injection of synthetic LH-RH during the early period of diestrus 2. The mean volume of primary oocytes of the three largest follicles at 1.00 h on the day of diestrus 2 was significantly smaller than that at 1.00 h on the day of proestrus. However, shortly before ovulation, the mean volume of secondary oocytes in the preovulatory follicles from rats treated with synthetic LH-RH at 1.00 h on the day of diestrus 2 was approximately the same as that in the preovulatory follicles from rats treated with the agent at 1.00 h on the day of proestrus. Shortly after ovulation the number of mitotic cumulus cells around the oviductal ova was significantly greater in advanced ovulation group induced by synthetic LH-RH injection during the early period of diestrus 2 than in spontaneous ovulation group. Furthermore, when examined 13 h after ovulation, the layers of cumulus cells were thicker, and cumulus cells were more tightly arranged around the ova in the advanced ovulation group induced by injection of synthetic LH-RH during the early period of diestrus 2 than those in the group with spontaneous ovulation. These results suggest that the cumulus-oocyte complex from advanced ovulation group induced by injection of synthetic LH-RH in the early period of diestrus 2 is less potent in fertilizability than that from spontaneous ovulation group, leading to a reduction in the rate of subsequent pregnancy.

ISSN:0378-7346    

DOI:10.1159/000299428

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

As part of a gynecological-andrological cooperation programme for the treatment of infertile marriages made by the 1st Department of Obstetrics and Gynecology and the Department of Urology, University of Vienna Medical School, the pregnancy rates achieved through 1,269 homologous inseminations of pathological ejaculates (according to Elliason’s classification) both with and without addition of kallikrein was analysed retrospectively. In the case of 131 married couples, only 5 pregnancies occurrred without the addition of kallikrein, and where kallikrein was used, there were also 5 pregnancies in 75 couples (6.66%). No conception occurred when cryoejaculate was used in addition. There were altogether 11 cases of spontaneous pregnancies. Conception could only be induced if an ejaculate of relatively high quality with a spermatozoa count of more than 12 million/ml and a 2-hour motility of more than 28% was used for insemination. The problems associated with homologous insemination with pathological ejaculate are being discussed.

ISSN:0378-7346    

DOI:10.1159/000299429

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

An unspecified region of the uterus of 7 healthy pregnant patients at term, not yet in labor, was mechanically distended by extraamniotic application of rubber bougies. In all cases, significant onset of labor was noted within 20 min to 5 h, cervical softening progressed with time, and delivery was achieved within 21 h. Significant elevation of prostaglandin E (PGE) and F (PGF) levels in amniotic fluid was noted with the progress of cervical dilatation. It appears that the release of PGE and PGF is dependent on uterine stretching and/or the subsequently induced uterine contractions. A possible source of the release of PG in the present study was discussed.

ISSN:0378-7346    

DOI:10.1159/000299430

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

Mouse placental cells have been isolated and grown in cultures. These cells produce a procoagulant which is identical to thromboplastin (factor III) by two criteria. The procoagulant activity increases with time, culminating on the 5th day of culture. The increase is inhibited by cycloheximide, α-amanitin, and actinomycin D, showing that de novo synthesis of protein and RNA is neccessary. About 90–95% of the total cellular thromboplastin activity in whole cells is available for inactivation by particle-bound trypsin and thus present on the cell surface. Endotoxin and phytohaemagglutinin did not further increase the procoagulant activity.

ISSN:0378-7346    

DOI:10.1159/000299431

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299432

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299433

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299434

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299435

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000299436

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0378-7346    

DOI:10.1159/000283460

出版商:S. Karger AG    

年代:1902

数据来源: Karger