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11. |
Repeat HIV Testing, Risk Behaviors, and HIV Seroconversion Among Young Men Who Have Sex With MenA Call to Monitor and Improve the Practice of Prevention |
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JAIDS Journal of Acquired Immune Deficiency Syndromes,
Volume 29,
Issue 1,
2002,
Page 76-85
Duncan MacKellar,
Linda Valleroy,
Gina Secura,
Brad Bartholow,
William McFarland,
Douglas Shehan,
Wesley Ford,
Marlene LaLota,
David Celentano,
Beryl Koblin,
Lucia Torian,
Thomas Perdue,
Robert Janssen,
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摘要:
ObjectivesWe compared recent risk behaviors and HIV seroconversion among young men who have sex with men (MSM) who were first-time, infrequent, and repeat HIV testers.MethodsMale adolescents and young men aged 15 to 22 years were randomly sampled, interviewed, counseled, and tested for HIV at 194 gay-identified venues in seven U.S. cities from 1994 through 1998. Analyses were restricted to MSM who reported having never tested or last tested HIV-negative.ResultsOf 3430 participants, 36% tested for the first time, 39% had tested infrequently (one or two times), and 26% had tested repeatedly (≥three times). Compared with first-time testers, repeat testers were more likely to report recent risk behaviors and to acquire HIV (7% versus 4%). Over 75% of repeat testers who seroconverted acquired HIV within 1 year of their last test. Compared with repeat testers, first-time testers reported similar use of health care but delayed testing for nearly 2 additional years after initiating risk.ConclusionsMany young MSM soon acquire HIV after repeated use of HIV counseling and testing services. Providers must strengthen practices to identify, counsel, and test young MSM and provide enhanced behavioral interventions for those with persistent risks.
ISSN:1525-4135
出版商:OVID
年代:2002
数据来源: OVID
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12. |
Incarceration and Risk for HIV Infection Among Injection Drug Users in Bangkok |
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JAIDS Journal of Acquired Immune Deficiency Syndromes,
Volume 29,
Issue 1,
2002,
Page 86-94
Kachit Choopanya,
Don Des Jarlais,
Suphak Vanichseni,
Dwip Kitayaporn,
Philip Mock,
Suwanee Raktham,
Krit Hireanras,
William Heyward,
Sathit Sujarita,
Timothy Mastro,
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摘要:
ObjectiveTo assess potential multiple relationships between incarceration and HIV infection among injecting drug users (IDUs) in Bangkok. Previous cross-sectional studies have shown strong relationships between incarceration and HIV infection but have not been able to assess potential causal pathways.MethodsInjection drug users seen at methadone treatment programs in Bangkok were screened during 1995 to 1996 for enrollment into the study. With informed consent, 1,209 seronegative IDUs were enrolled in a cohort study to determine HIV incidence and identify factors associated with incident infections. Follow-up visits were conducted every 4 months, with HIV testing and assessment of risk behaviors.ResultsOverall incidence rate was 5.8 per 100 person-years (95% confidence interval [CI], 4.8–6.8) of follow-up. A four-step “injection risk” scale was constructed that included less frequent than daily injection, daily injection, daily injection with reported sharing of injection equipment, and injection while incarcerated. This scale was strongly related to HIV incidence, with incidence approximately doubling for each step in the scale. Incidence rate for follow-up periods that contained drug injection while incarcerated was 35/100 person-years at risk. In multivariate analyses, incarceration was related to incident HIV infection in multiple ways: previous incarceration and recent incarceration without drug injection, and the injection risk scale were all independently predictors of incident HIV infection.ConclusionsIncarceration is related to incident HIV infection through multiple pathways. Previous incarcerations are likely to serve as markers for unmeasured high-risk behaviors, and it is also highly likely that HIV is transmitted during periods of incarceration. Programs to reduce HIV transmission in jails and prisons, including drug abuse treatment of inmates and programs to reduce the likelihood of incarceration of IDUs, are needed urgently. Given the current diffusion of injecting drug use, of HIV infection among drug injectors, and of the common policy of incarcerating drug users, it is very likely that the problem of HIV transmission in jails and prisons is increasing in many countries throughout the world.
ISSN:1525-4135
出版商:OVID
年代:2002
数据来源: OVID
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13. |
The Association of Socioeconomic Status and Use of Crack/Cocaine With Unprotected Anal Sex in a Cohort of Men Who Have Sex With Men in Rio de Janeiro, Brazil |
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JAIDS Journal of Acquired Immune Deficiency Syndromes,
Volume 29,
Issue 1,
2002,
Page 95-100
Claudia Teresa de Souza,
Theresa Diaz,
Frits Sutmoller,
Francisco Bastos,
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摘要:
To evaluate the relation between illicit drug use, sexual practices, and socioeconomic status, we analyzed data from the baseline interview of a cohort of 675 men who have sex with men conducted from 1994 to 1999 in Rio de Janeiro, Brazil. Bivariate analyses of factors associated with crack/cocaine use with sex revealed that men who reported crack/cocaine use were significantly (p< .05) more likely than men who did not report drug use to be unemployed (42.7% vs. 29.1%), to have an income of <$250 per month (70.7% vs. 60.9%), to have <8 years of education (69.5% vs. 50.9%), to report bisexual activity (81.7% vs. 41.7%), and to engage in commercial sex (72.0% vs. 37.9%). Multivariate analysis of factors associated with unprotected anal sex with casual male partners in the last 6 months demonstrated that the following variables were associated with this outcome: an income <$250 per month (adjusted odds ratio [AOR] = 1.73, 95% confidence interval [CI]: 1.04–2.87), less than 8 years of education (AOR = 2.21, CI: 1.38–3.53), a greater sense of vulnerability (AOR = 2.58, CI: 1.54–4.33), a willingness to participate in vaccine trials (AOR = 1.91, CI: 1.20–3.05), and use of crack/cocaine (AOR = 1.91, CI: 1.05–3.46). Our findings suggest that HIV prevention programs for these men need to address drug use and how drug use may influence sexual behaviors.
ISSN:1525-4135
出版商:OVID
年代:2002
数据来源: OVID
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14. |
Pharmacokinetic Variability Caused by Gender: Do Women Have Higher Indinavir Exposure Than Men? |
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JAIDS Journal of Acquired Immune Deficiency Syndromes,
Volume 29,
Issue 1,
2002,
Page 101-102
David Burger,
Marijke Siebers,
Patricia Hugen,
Rob Aarnoutse,
Yechiel Hekster,
Peter Koopmans,
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ISSN:1525-4135
出版商:OVID
年代:2002
数据来源: OVID
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15. |
Multidrug-Resistant HIV-1 RNA and Proviral DNA Variants Harboring New Dipeptide Insertions in the Reverse TranscriptasepolGene |
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JAIDS Journal of Acquired Immune Deficiency Syndromes,
Volume 29,
Issue 1,
2002,
Page 102-104
Laurent Andréoletti,
Laurence Weiss,
Ali Si-Mohamed,
Christophe Piketty,
Thierry Prazuck,
Gérard Calamy,
Jean-Elie Malkin,
Mathieu Matta,
François-Xavier Mbopi-Kéou,
François Clavel,
Michel Kazatchkine,
Laurent Bélec,
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ISSN:1525-4135
出版商:OVID
年代:2002
数据来源: OVID
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16. |
How Many People Are at Risk for HIV in the United States? The Need for Behavioral Surveys of At-Risk Populations |
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JAIDS Journal of Acquired Immune Deficiency Syndromes,
Volume 29,
Issue 1,
2002,
Page 104-105
John Anderson,
Ron Stall,
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ISSN:1525-4135
出版商:OVID
年代:2002
数据来源: OVID
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17. |
Excess Mortality From Liver Disease and Other Non–AIDS-Related Diseases Among HIV-Infected Individuals in Italy |
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JAIDS Journal of Acquired Immune Deficiency Syndromes,
Volume 29,
Issue 1,
2002,
Page 105-107
Susanna Conti,
Maria Masocco,
Patrizio Pezzotti,
Virgilia Toccaceli,
Monica Vichi,
Roberta Crialesi,
Luisa Frova,
Giovanni Rezza,
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ISSN:1525-4135
出版商:OVID
年代:2002
数据来源: OVID
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