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| 1. |
The Molecular Basis of MHC-Restricted Antigen Recognition by T Cells |
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International Reviews of Immunology,
Volume 3,
Issue 3,
1988,
Page 147-174
SaitoTakashi,
GermainRonald N.,
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摘要:
In order to determine the contribution of the clonotypic T cell receptor (Ti)αβheterodimer to the antigen/MHC specificity of mature T cells, we have transfected cloned Tiαand/orβgenes into either human or mouse T cells, and analyzed the transfectants for Ti-T3 expression and responses to antigen and la molecules. Our analysis establishes that a single receptor structure (the Tiαβheterodimer) is necessary and sufficient to define the dual specificity of T cell antigen recognition and suggests that in at least certain instances Tiβchains play a predominant role in MHC restriction specificity, raising the possibility of a“one receptor, two sites”model of T cell recognition.
ISSN:0883-0185
DOI:10.3109/08830188809051187
出版商:Taylor&Francis
年代:1988
数据来源: Taylor
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| 2. |
Characterization of Antigen-Binding Molecules from T Suppressor Hybridomas |
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International Reviews of Immunology,
Volume 3,
Issue 3,
1988,
Page 175-204
ChanAgnes,
StammersAnthea Tench,
NorthJanice,
SteeleJ. Kevin,
ChuN. Randall,
LevyJulia G.,
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ISSN:0883-0185
DOI:10.3109/08830188809051188
出版商:Taylor&Francis
年代:1988
数据来源: Taylor
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| 3. |
T Cell-Derived Antigen Binding Molecules (TABM): Molecular and Functional Properties |
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International Reviews of Immunology,
Volume 3,
Issue 3,
1988,
Page 205-228
ConeRobert E.,
ZhengHeguang,
ChueBen,
BeamanKenneth,
FergusonThomas,
GreenDouglas R.,
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ISSN:0883-0185
DOI:10.3109/08830188809051189
出版商:Taylor&Francis
年代:1988
数据来源: Taylor
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| 4. |
Molecular Analysis of Suppressor T Cell Receptors |
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International Reviews of Immunology,
Volume 3,
Issue 3,
1988,
Page 229-239
TaniguchiMasaru,
ImaiKenji,
KosekiHaruhiko,
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PDF (533KB)
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ISSN:0883-0185
DOI:10.3109/08830188809051190
出版商:Taylor&Francis
年代:1988
数据来源: Taylor
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| 5. |
Conservation of Immunoglobulin Variable and Joining Region Structure and the Design of Universal Anti-Immunoglobulin Antibodies Reactive with Antigen-Binding T Cell Receptors |
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International Reviews of Immunology,
Volume 3,
Issue 3,
1988,
Page 241-273
MarchalonisJohn J.,
SchluterSamuel F.,
HubbardRoger A.,
DiamandurosAndrew,
BarkerWinona C.,
PumphreyRichard S. H.,
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PDF (1518KB)
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ISSN:0883-0185
DOI:10.3109/08830188809051191
出版商:Taylor&Francis
年代:1988
数据来源: Taylor
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