ISSN:0148-639X    

DOI:10.1002/mus.880010502

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractEarly investigations into sensory conduction are reviewed and related to recent and ongoing research, specifically with relation to the early detection of nerve disorders. Current study on entrapment neuropathies and on the assessment of minor sensory conduction changes is presented. It is concluded that, in the early recognition of nerve disease, the clinical orientation of the electromyographer is essential to proper test interpretation.

ISSN:0148-639X    

DOI:10.1002/mus.880010503

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractEvaluated herein are the advantages and limitations of recording sensory action potentials with a gross electrode placed near the nerve. This technique has proved to be a sensitive measure of early nerve damage for two reasons: first, electrodes can be positioned in such a way that maximal velocity is determined only along the abnormal stretch of the nerve; and second, small late components originating from demyelinated, remyelinated, or regenerating fibers can be detected.

ISSN:0148-639X    

DOI:10.1002/mus.880010504

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractHistologic findings are described in nerves from men exposed to lead, from patients with discrete clinical signs of peripheral neuropathy, and from controls. Every nerve from control subjects showed an abnormality (paranodal remyelination, segmental remyelination, or regeneration) in teased fibers. The only histologic alteration in eight lead‐exposed males without signs or symptoms of neuropathy was a slightly increased incidence of paranodal remyelination. Sixteen patients with discrete neurologic symptoms and signs had a loss of large myelinated fibers and an increased incidence of regenerated fibers among teased fibers. Electron microscopy of unmyelinated fibers showed an increased occurrence of Schwann‐cell processes, of fibers undergoing degeneration, and of Schwann‐cell subunits with many profiles as the earliest signs of abnormality. Clinically mild neuropathies may exhibit advanced regeneration in the case of unmyelinated fibers. The earliest sign of degeneration in myelinated fibers was a diminution in the number of axonal organ

ISSN:0148-639X    

DOI:10.1002/mus.880010505

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractAn attempt is made to evaluate available information regarding the integrity of unmyelinated fibers, particularly somatic unmyelinated fibers in man and in other primates, with relation to early recognition of nerve disorders. Discussion is limited to morphologic aspects of these fibers.

ISSN:0148-639X    

DOI:10.1002/mus.880010506

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractThe stability of sensory conduction and evoked potentials during ischemia has been used in the evaluation of diabetic neuropathy and diabetic control (Hgb A1C). Six newly diagnosed juvenile diabetics were studied at diagnosis and 3 to 12 months later. In three patients in good control, ischemic “resistance” became normal. In three patients in poor control, resistance remained increased; two of these three experienced a 10%–20% slowing in conduction velocity. Similar relationships between control and ischemic resistance are found in long‐term diabetics. These data suggest that abnormal ischemic resistance may herald the onset of an electrical and clinical neuropathi

ISSN:0148-639X    

DOI:10.1002/mus.880010507

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractIn the investigation of subclinical or minimal toxic neuropathies, selection of the proper electrophysiological test depends largely on the nature of the condition being studied. Examples are given of several toxic disorders, and their features are discussed in relation to the appropriate electrophysiological measurement.

ISSN:0148-639X    

DOI:10.1002/mus.880010508

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractObservations were made on the occurrence of peripheral neuropathy in a series of 139 patients admitted to a chronic dialysis program over a 10‐year period. Evidence of neuropathy was obtained in approximately 50% of these patients over the total period. Once dialysis was instituted, distal paresthesiae evident before the inception of dialysis tended to clear rapidly. Occurrence of the symptom of “restless legs” correlated positively with the presence of neuropathy. Persistent neuropathy was more commonly sensory than motor, and its features were consistent with a predominant loss of large myelinated fibers. This analysis suggests that multiple factors may be involved in the origin of uremic neuro

ISSN:0148-639X    

DOI:10.1002/mus.880010509

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractFibrillation potentials and positive sharp waves were recorded in the paralyzed muscles of 31 patients with a conduction block of more than 14 days' duration. In 75% of the muscles, these effects were attributed to axonal damage in addition to the local demyelinating block, this conclusion being based on changes in the properties of the motor unit found electromyographically when recovery had taken place. In the remaining 25% of the muscles, the denervation‐like activity was thought to be an effect of the local demyelinating block alone. The delay of the sensory action potential recorded above the presumed site of nerve compression most likely arises from a block of the largest myelinated nerve fibers. This assumption is based on the fact that the amplitudes of the fastest‐ and the slower‐conducted components in the patients differed little from corresponding components in the normal

ISSN:0148-639X    

DOI:10.1002/mus.880010510

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY

摘要:

AbstractMechanisms involved in maintaining bulk and strength in partially denervated muscles of patients with neurogenic lesions are discussed. Estimation of muscle fiber hypertrophy by electrophysiological examination is possible, but it depends on the construction of sampling electrodes with precise geometry. The arrangement of muscle fibers of motor units within the muscle is discussed by analogy with the four‐color map problem. An experiment to measure the twitch tensions of individual motor units in man is devised; it requires the use of microprocessor control of the stimulus and recurrent measurements of the twitch force

ISSN:0148-639X    

DOI:10.1002/mus.880010511

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1978

数据来源: WILEY