ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04885.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

A case–control study of maternal age as a risk factor for Alzheimer's disease was conducted in Washington state. Clinically diagnosed cases of Alzheimer's disease (n= 64) were identified from two sources, an outpatient clinic at the University of Washington and an organization of relatives of patients with Alzheimer's disease. Controls were spouses of the Alzheimer's disease cases and spouses of 87 patients with Parkinson's disease, also identified at the University of Washington. Mail questionnaires were sent to all subjects; responses were received for 90 cases and 96 controls, although nine of those cases, whose medical records of diagnostic evaluations were incomplete, were excluded. Among the 69 cases and 94 controls whose mothers' ages were known, there was no evidence that the mothers of cases were significantly older than the mothers of controls (chi‐square test for trend,P= 0.82). These findings do not support the theory that persons born to older mothers are at increased risk of developing Alzheimer's dise

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04886.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

The clinical and microbiologic features of septic arthritis in 23 elderly patients are reviewed. Fifteen patients had pre‐existing joint diseases, predominantly osteoarthritis and rheumatoid arthritis. Eight patients had underlying systemic illnesses, and eight patients were receiving systemic corticosteroid therapy prior to the development of septic arthritis. The knee was the joint most commonly infected. AlthoughStaphylococcusaureus was the major pathogen (52.2 per cent of patients), enteric gram‐negative bacilli were found in seven of 23 patients (30.4 per cent). Five patients died (21.7 per cent mortality), two as a result of their infection and three of nosocomial Pseudomonas sepsis. Eight of the 18 survivors (44.4 per cent) developed osteomyelitis in the contiguous bone. Return of joint function was slow in all patients. Septic arthritis in the elderly is difficult to treat and has a poor outcome, possibly because pre‐existing joint disease is very common and enteric gram‐negative bacilli are often the causative or

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04887.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

To improve the pneumococcal vaccination status of an elderly patients group, those older than 64 years of age were identified from a computer file of all continuing care patients in a general internal medicine clinic. In a randomly chosen study group (N= 163), 91 elderly patients (56 per cent) had received the pneumococcal vaccine. Factors associated with a higher rate of pneumococcal vaccination included receiving the previous year's influenza vaccine, a medical problem list attached to the patient's chart, active clinic status (i.e., seen in the year before the study began), and more than two problems listed in the computer record. Letters encouraging pneumococcal vaccination were then sent to patients who had not been vaccinated. Twenty of 72 patients (28 per cent) who received the letter were vaccinated during the next year; 8 per cent of control patients (three of 39) who did not receive the letter were vaccinated. The 95 per cent confidence limit for the relative difference between the study and control group is 6 to 53 per cent. The relative difference was also significant for influenza vaccination between the intervention group and the portion of the control group that had not been vaccinated at the first chart review. Factors associated with pneumococcal vaccination rate following the mailing of the reminder letter were active clinic status and being up to date for either influenza or tetanus vaccination. The incidence of complete vaccination (pneumococcal, influenza, and tetanus) did not improve significantly in the study population. It is concluded that pneumococcal vaccination prevalence increases significantly when patients are sent letters encouraging vaccination.

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04888.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Several examples of physicians' ethical and legal responsibilities toward older individuals desiring medical care are discussed. The focus is on the older person's ethical and legal right to access to medical services, and on the extent of corresponding obligations of physicians to actuate and fulfill the older person's access rights. The impact of current cost constraints in carrying out these obligations is also discussed.

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04889.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04890.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04891.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04892.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04893.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1985.tb04894.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY