摘要:

AbstractThis report concerns the amount of age‐dependent lipofuscin in the myocardium (left ventricle) as found at autopsy in a group of 54 persons who had been exposed proximally (1,400 meters from the hypocenter) to the Hiroshima and Nagasaki atomic bombs of 1945. The subjects were matched by sex and age‐decade of death with a similar number of subjects who were in neither city at the time of the explosions. The results failed to demonstrate an accelerated accumulation of pigment in the proximally exposed group. Although the difference was not statistically significant, the majority of the exposed group appeared to accumulate lipofuscin more slowly than did the nonexposed group. The possible implications are discus

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02621.x

年代:1971

数据来源: WILEY

摘要:

“Not yet can I speak with the authority of the ”retired“ from labour, a shadowy company who spend their time in regretting their retirement and criticising their successors. I am still at work with my hand to the plough, and my face to the future. The shadows of evening, it is true, lengthen about me, but morning is in my heart!”Sir William Mulo

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02622.x

年代:1971

数据来源: WILEY

摘要:

AbstractIn a controlled double blind study, 40 geriatric patients with cerebrovascular disorders were treated with sublingual tablets of Hydergine or placebo for twelve weeks. The inventory of symptoms (32 items) included an array which portrayed their physical status, behavioral traits, and intellectual impairments. Final appraisals based on re‐evaluations at three‐week intervals during treatment showed that, compared to the placebo, Hydergine produced greater improvements in 19 of the 30 items rated. The most impressive results ascribable to Hydergine pertained to cognition and intellectual function. No untoward effects from this drug were observed during the course of this study. A probable mode of action of this ergot preparation is also discus

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02623.x

年代:1971

数据来源: WILEY

摘要:

AbstractThis is an outline, based on Swedish conditions, of an organisation created to help long‐term (LT) patients. As geriatric LT‐patients form a steadily growing problem for the Western world, it is essential to find a way in which the community can help them and, at the same time, help itself.The LT‐speciality requires a change in the work of the hospital physician. First of all its requires that he become acquainted with the social organisation of the community and the possibilities for obtaining help. This is an important part of the whole work if he is to start and carry through the necessary co‐operation with the central and local authorities.If a community does not find a satisfactory solution to the problem of the necessary help for LT‐patients, all the health services and the whole of the welfare program will suffer

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02624.x

年代:1971

数据来源: WILEY

摘要:

AbstractScleroderma, hitherto rarely reported in patients beyond the age of 70, is not uncommon among female patients of the geriatric age group. The author observed 15 cases during eleven years of geriatric practice.In all the cases the disease was in a mild form and appeared to have a favourable prognosis. Of the 15 patients, 2 were definitely, and an additional 8 were probably cases of the CRST syndrome—calcinosis, Raynaud's phenomenon, sclerodactyly, and telangiectasia. Thus the CRST syndrome, previously regarded as a rare benign variant form of scleroderma, seems to be common in the elderly and to represent the most frequently observed form of the disease. The remaining 5 cases, showing only Raynaud's phenomenon and skin changes (oesophageal changes occasionally), may represent incomplete forms of the CRST syndrome, as they were of shorter duration but differed in no other essential respects.It is suggested that the CRST syndrome may represent merely a late stage of acrosclerosis and not a separate disease entit

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02625.x

年代:1971

数据来源: WILEY

摘要:

AbstractThe effect of transfer from one nursing home to another was studied in 82 male veterans over a four‐year period. Group T comprised 41 patients who were transferred from the initial nursing home to one or more other homes; Group NT (controls) comprised 41 patients who were not transferred from the initial nursing home. Disability and illness were assessed by specific rating scales, and the 32 nursing homes were evaluated by three social workers. There were no significant differences between the two groups of patients, although the NT group seemed more disorganized at the end of the study period. For the transferred group there was no increase in the mortality rate. Apparently the most important factor in good adjustment to a nursing home is the understanding of the patient's needs for assistance and servic

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02626.x

年代:1971

数据来源: WILEY

摘要:

AbstractCase histories are presented to illustrate problems posed by elderly patients with rheumatic disease. When the diagnosis of rheumatoid arthritis or osteoarthritis is established, various medical or surgical measures are applicable (as described). In another group of patients, the differential diagnosis is more difficult, but must be solved before proper treatment can be started.

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02627.x

年代:1971

数据来源: WILEY

摘要:

AbstractPyelonephritis is an extremely complex disease and is not fully understood. In its development, it gives rise to a great variety of signs and symptoms and involves a series of pathogenic mechanisms. This article explores the various aspects of urinary‐tract infections in the light of our present knowledge. Topics of discussion are the common causes of pyelonephritis, the collection and bacteriologic study of the urine, the use and abuse of the catheter, pathways of infection, the special susceptibility of certain age groups (including the elderly) to infection, diagnostic procedures, and medical and surgical therap

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02628.x

年代:1971

数据来源: WILEY

摘要:

AbstractIf glucose intolerance or early maturity‐onset diabetes are to be detected, all adults, even if there is no family history of diabetes, should be tested. A study was made of 489 ambulatory, relatively “healthy” adult patients. They were screened for the detection of diabetes and decreased glucose tolerance, and 300 standard three‐hour oral glucose tolerance tests (OGTTs) were also performed. Urinary glucose determinations were made concomitantly.Details of the analytical procedures are given. Standardized dietary preparation is stressed. Formulae for converting whole‐blood glucose values to plasma values are presented. The Wilkerson diagnostic criteria seem the most appropriate for general use.From 5 to 15 per cent of the adults with normal OGTT values had significant glucosuria. The percentage incidences of glucose intolerance and of diabetes increased with age. Patients with 4‐plus glucosuria (quantitatively, at least 2 per cent) should be considered diabetic until proved otherwise, even though the glucose tolerance curve may be normal, since the height of the curve may be related to the low renal threshold. Adults with a significant degree of glucose intolerance need treatment, whether the intolerance be due to diabetes mellitus, or secondary to some other primary disease, or caused by certain therapeutic measures (e.g., surg

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02629.x

年代:1971

数据来源: WILEY

摘要:

AbstractWith advancing age, the electrocardiographic P‐R interval lengthens. The question arises as to whether this characteristic of the aging process can be regarded asnormalor asphysiologic. Two hundred and fifty dentists and their wives were studied, before and after an improved dietary regimen. Comparisons were made with Lepeschkin's data on 872 “normal” persons. On the assumption that normal is synonymous with average, there is normally an increase in the length of the P‐R interval. However, the data in this report suggest that a progressively longer P‐R interval with time is not physiologic. Moreover, the trend can be reversed by dietary means. Thus people can be made “younge

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1971.tb02630.x

年代:1971

数据来源: WILEY