摘要:

ABSTRACTCardiac amyloid accumulation is a common autopsy finding in elderly persons, the frequency increasing with each advancing age decade. In most cases the deposits are microscopic, confined to the atrial subendocardium, and of dubious significance. In a few cases, however, there is much more extensive cardiac involvement, with infiltration of the ventricular musculature and intracardiac conduction system. In the authors’ recent autopsy study of 100 patients over 60 years of age, 10 had diffuse cardiac amyloidosis with biventricular involvement. Microscopically, the amyloid deposits often resembled foci of interstitial fibrosis. Significant cardiac enlargement (weight>380 gm) was present in only 2 of these patients, and in only one of them were the clinical signs and symptoms clearly attributable to the amyloid infiltration. It was difficult to assess the possible contribution of ventricular amyloid to congestive failure since most of the patients also had coronary arteriosclerosis.In the aged, clinically significant cardiac amyloidosis associated with cardiac enlargement appears to be part of a disease spectrum more commonly characterized by focal, clinically insignificant cardiac amyloid deposits. Yet several features suggest that senile cardiac amyloidosis may differ from the clinically significant cardiac amyloidosis occasionally seen in younger patient

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00968.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTA survey conducted at 12 VA hospitals included the collection of detailed information on the use of psychoactive drugs in 1,276 elderly psychiatric patients. On the day of the survey, 61 per cent of the patients were receiving psychoactive drugs. Prescription practices relating to the choice of drugs, prevalence of drug use, dosage, combination drug preparations, and antiparkinson agents are discussed in terms of such factors as the patient's age and the diagnosis. Also discussed is the literature on psychoactive drugs, particularly as it pertains to elderly populations.

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00969.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTCardiovascular diseases and their treatment in the aged are discussed under the headings of ischemic heart disease, hypertension, cardiac failure (with special reference to the use of diuretics and digoxin), infective carditis and thyroid disorders. Advanced age modifies the approach to treatment; the choice of drugs and the dosage must be adjusted accordingly. Possible drug interactions should also be considered. A rehabilitation program is of great benefit for many elderly cardiac patients. It should be planned individually and involve psychologic and environmental factors as well as medical therapy. After successful treatment of the acute episode, even the aged patient can undertake rewarding activities in his remaining lifetime.

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00970.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTThe prevalence of coronary risk factors was assessed in 2,524 asymptomatic adults in Long Beach, California. Hypercholesterolemia (serum cholesterol level>250 mg/100 ml) was present in 725 subjects (28.8 per cent), hypertriglyceridemia (serum triglyceride level ≥150 mg/100 ml) in 497 (19.7 per cent), and an abnormal lipoprotein pattern in 813 (32.2 per cent). Of the 2,524 subjects, 233 (9.2 per cent) had a blood pressure above 140/90 mm Hg and 116 (4.6 per cent) has a blood pressure above 150/100 mm. There were 1,043 cigarette, cigar, or pipe smokers (41.3 per cent). Fifty subjects (2.0 per cent) had a fasting blood sugar level above 120 mg/100 ml, 48 (1.9 per cent) had abnormal triceps skinfold thickness, and 382 (15.2 per cent) weighed 20 per cent or more above the desirable weight. The electrocardiogram during rest was definitely abnormal in 183 subjects (7.3 per cent). On the basis of these data it is evident that in many asymptomatic adults, risk factors predisposing to coronary disease are not being detected or treate

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00971.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTThe occurrence of anemia in a group of aged persons residing in a home for the aged and in a chronic disease hospital was reviewed with regard to etiology, choice of treatment, and therapeutic response. Of the 484 patients, 151 (31 per cent) had anemia or were receiving antianemia therapy. Iron‐deficiency anemia was the most common type, and iron was the most common form of treatment. Seventy‐eight patients were given antianemia therapy in 97 courses, and a good therapeutic result was achieved in about one‐fourth of the courses. The most frequent error in iron therapy was its use in the anemia associated with chronic disorders. Often there was a combination deficiency of iron, vitamin B12 and folic acid. The response to iron in the elderly can be very slow, so therapy should not be discontinued too soon. Anemia may directly contribute to other serious pathologic conditions, especially in aged persons with impaired circulation. In some cases the physiologic concentration of hemoglobin may be higher than the accepted “normal” value. The course of the anemia in relation to the general state of the patient is more significant than any laboratory data in choosing antianemia therapy. Practical laboratory screening procedures for elderly anemic patients are

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00972.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTThe entire general medical unit of Ste. Anne's Hospital for disabled elderly veterans was moved into a new modern building on July 13, 1971. Roughly, about 350 patients were involved. In anticipation of the move, a program of preparation of the patients was organized to prevent if possible the dramatic increases in the mortality rate reported in some earlier studies of relocated geriatric populations. The principal finding with regard to mortality was a significant decrease of 6.82 per cent after the relocation when compared with the mortality rate for the previous year. The highly appreciated air‐conditioning system in the new building, representative of modern improvements, may have helped to a minor degree. A much more important factor was the well organized program for preparation of the patients, skillfully carried out by a conscientious staf

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00973.x

年代:1975

数据来源: WILEY

摘要:

ABSTRACTThe psychosomatic rehabilitation of the elderly is an important task from both social and economic viewpoints. For psychic rehabilitation, moderate activity and the playing of games (such as chess, dominoes or cards) are recommended. Based on experiences with a group of 50 persons of the 70–90 age group, bridge playing is an especially desirable form of recreation. For somatic rehabilitation, physical exercise is a valuable aid, based on experiences with 338 partially disabled patients of the 51–81+ age gr

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00974.x

年代:1975

数据来源: WILEY

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00975.x

年代:1975

数据来源: WILEY

ISSN:0002-8614    

DOI:10.1111/j.1532-5415.1975.tb00976.x

年代:1975

数据来源: WILEY