ISSN:0007-1323    

DOI:10.1002/bjs.1800770502

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

ISSN:0007-1323    

DOI:10.1002/bjs.1800770503

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

ISSN:0007-1323    

DOI:10.1002/bjs.1800770504

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

摘要:

AbstractThere is accumulating evidence that multiple organ failure is not always the result of an established septic focus. Increasing attention has centred on the gut as a reservoir of bacteria (and bacterial endotoxins) that can traverse the intestinal mucosal barrier (a process called ‘bacterial translocation’) and initiate the septic state. Although the link between haemorrhagic shock and sepsis was recognized decades ago, the full experimental demonstration of this phenomenon is more recent. It was shown to occur in three main settings: physical disruption of the gut mucosa, impaired defence mechanisms and altered gut microbial ecology. Conditions such as haemorrhagic shock, burns, protein malnutrition and sepsis are seen in the severely ill surgical patient or the multiply injured, and are known to cause various combinations of circumstances favourable to bacterial translocation and endotoxin absorption. These may play an important role in the mortality of the critically

ISSN:0007-1323    

DOI:10.1002/bjs.1800770505

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

摘要:

AbstractThe sexual practices of male homosexuals may lead to the development of a wide variety of colorectal and perianal diseases. This review describes the pathogenesis of these conditions, their management, and the influence of HIV infection on these conditions.

ISSN:0007-1323    

DOI:10.1002/bjs.1800770506

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

摘要:

AbstractTrauma centre standards of the American College of Surgeons set a minimum annual volume of cases for trauma surgeons. The volume requirement, however, lacks an objective basis. The author reviews a personal series of cases revealing considerably lower volume than recommended, while injury severity and mortality were comparable to published data. No death was considered preventable on review. Possibly, lower individual caseloads are acceptable for trauma surgeons.

ISSN:0007-1323    

DOI:10.1002/bjs.1800770507

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

摘要:

AbstractThe incidence of synchronous and metachronous liver metastases in patients with colorectal cancer is extremely high. Approximately 25 per cent of patients will have overt liver metastases at the time of presentation, and in the remainder up to 40 per cent will eventually develop liver metastases. In an attempt to obtain a prognostic index for the prediction of those patients most likely to develop liver metastases, 134 patients with primary colorectal cancer but without overt liver metastases at initial presentation were followed up for between 5–10 years. Regular liver scans were performed and the presence of liver metastases observed. A total of 47 patients developed liver metastases. Those preoperative variables related to the subsequent development of liver metastases were sex, log10serum alkaline phosphatase level and Dukes' classification. A prognostic index using these parameters has been calculate

ISSN:0007-1323    

DOI:10.1002/bjs.1800770508

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

摘要:

AbstractDuring the period 1943–67, 903 Danish patients aged<40 years had colorectal carcinoma. The patients were followed up for up to 41 years and during this period 44 of 501 (9 per cent) operated on for cure developed a metachronous colorectal carcinoma. The cumulative risk of a metachronous colorectal carcinoma was 30 per cent after up to 41 years of observation. The occurrence of a metachronous colorectal carcinoma was evenly distributed in the observation period. The cumulative survival rate after operation for a metachronous colorectal carcinoma was 41 per cent after 20 years of observation. We propose a lifelong follow‐up programme after resection of colorectal carcinoma for cure in this age group, including annual Hemoccult® test and colonoscopy at 3‐year int

ISSN:0007-1323    

DOI:10.1002/bjs.1800770509

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

摘要:

AbstractThe incidence of dysplasia in the mucosal strippings from the anorectal stump was studied in 132 patients treated by restorative proctocolectomy with Heal reservoir for ulcer at ive colitis and familial adenomatosis. The anorectal mucosa was stripped from the level of division of the gut tube to the dentate line. Of 118 patients with ulcerative colitis, 12 (10–2 per cent) had dysplasia in some part of the large bowel. Mucosal strippings were examined histologically in 118 cases, of which only three (2–5 per cent) showed dysplasia. There was a correlation between dysplasia and the presence of carcinoma and the duration of the disease in the operative specimen of colon and rectum and also in the anorectal mucosal specimen although the number of patients with carcinoma (eight cases) in this analysis was small. All 14 patients with familial adenomatous polyposis showed large bowel mucosal dysplasia in the operative specimen which was severe in six cases. Anorectal mucosal strippings were examined in these patients and 12 showed dysplasia which was severe in th

ISSN:0007-1323    

DOI:10.1002/bjs.1800770510

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY

ISSN:0007-1323    

DOI:10.1002/bjs.1800770511

出版商:John Wiley&Sons, Ltd.    

年代:1990

数据来源: WILEY