摘要:

AbstractThree new cases of gynecological verrucous squamous cell carcinomas are reported; one in the uterine cervix, and two in the vulva. The English literature covering the 49 cases reported previously is surveyed with special reference to the diagnostic and therapeutic aspects of these tumors, as well as with their clinical behavior and possible relationship to viral (HPV) lesions (Condylomas) of the genital tract.It was concluded that so far the exact relationship between the different verrucous squamous cell lesions in the genital tract remains obscure, all such lesions should be regarded as potentially malignant, and treated accordingly by radical surgery.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90016-3

出版商:Wiley    

年代:2017

数据来源: WILEY

摘要:

AbstractThe case reported here shows how adequate conservative therapy of the antiestrogen R‐2323 saved a uterus in a woman of childbearing age who suffered a uterine leiomyoma. The patient's fertility was restored, and a twin pregnancy is currently in progress.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90017-5

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractSperm migration to the upper genital tract was studied in 15 volunteers who were to be surgically sterilized to see if sperm migration to the upper genital tract is consistent during different stages of the menstrual cycle. Five subjects underwent surgery during the midproliferative phase, five during the periovulatory period and five during the secretory phase. The stage of the cycle was determined by endometrial and ovarian biopsy at the time of surgery. Volunteers had a single coitus 5–12 h before surgery, confirmed by Sims‐Huhner test. Sperm were found in the uterus and at least one oviduct in all five subjects studied during the periovulatory phase, and only in two of the five cases undergoing surgery during either of the other phases. A good correlation was also observed between presence and number of sperm in the upper genital tract and quality of Sims‐Huhner test. However, neither the cycle stage nor the postcoital test had an absolute prognostic value over sperm migration.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90018-7

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractObstetrical features and antenatal findings in 68 pregnancies with fatal fetal abnormalities are evaluated. The course of the pregnancy was complicated in 81% of these cases, the most common complication being intrauterine fetal growth retardation (IUGR) which was typical for 18‐trisomies and multimalformed fetuses. The retardation in symphyseal‐fundal growth was manifested on the average on the 25th gestational week. Low‐profile type biparietal growth retardation was associated with 43% of the IUGR cases, and the brain‐sparing effect in growth was found in 29%. Polyhydramnios was a complication in 30% of the series. Premature labor was associated with 60% of the spontaneously initiated deliveries in the series, and was not due to the polyhydramniotic tendency only. Antenatal evaluation of the fetoplacental unit function revealed a normal capacity in 62% of the cases. The fatality of the fetal abnormality was not manifested in any special feature in the complications of the pregnancy. Antenatal etiological evaluation and search for fetal anomalies in all pregnancies complicated by early IUGR, polyhydramnios and imminent premature labor is stressed for the adequate assessment of perinatal care.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90019-9

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractLow‐dose endometrial after loading irradiation was used in 19 mentally retarded women for the induction of therapeutic amenorrhea. They were divided into two subgroups on the basis of age: 13 young patients (mean age 17 years, range 13–26 years) and six patients of middle age (mean age 42 years, range 34–44 years).In the young patients, during the 10‐month month follow‐up period, the plasma E2levels did not decrease. HOwever, the FSH concentration increased. Later on, 2–9 years after treatment, the E2levels were significantly higher than those of healthy postmenopausal women and did not differ from the values of healthy women in the sixth to seventh days of the menstrual cycle. At that time the FSH and LH levels were similar to reference values in reproductive age. The E2/E1ratio was significantly higher than that of healthy women in the sixth to seventh days of the cycle and that of postmenopausal women. Most of the menstrual cycles were anovulatory but some ovulatory also occurred. The testosterone concentrations did not differ from reference values. The ovaries of the middle age patients were more sensitive to irradiation than those of the younger patients.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90020-5

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractThe purpose of this study was to determine the extent of oral contraceptive (OC) exposure of women with secondary amenorrhea of hypothalamic‐pituitary etiology. In 93 of 126 women with secondary amenorrhea sufficient data were obtained regarding menstrual history and OC exposure: 26 patients had evidence of a prolactinoma, an additional 26 patients had idiopathic hyperprolactinemia without evidence of a pituitary tumor, and 41 had “pure” dysfunction hypothalamicpituitary amenorrhea. After stratification by age at diagnosis and parity the estimated odds ratio for past oral contraceptive usage showed no differences among the three groups (odds ratios between 0.74 and 1.48). Using the chisquare test the proportion of subjects who had regular menses before oral contraceptive intake and developed anovulation immediately after discontinuance (“post pill amenorrhea”) in the three groups also showed no difference (χ2= 0.60, P = 0.74). These data indicate that non‐ovulatory patients are likely to have been exposed to OC, and do not indicate that patients with prolactinomas differ in the extent of their OC exposure from other specified groups of patients with secondary amenorrhea.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90021-7

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractA woman with a septate vagina and two cervices was observed. One of the cervices ended blindly. The other cervix communicated with a normal corpus and two normally positioned patent fallopian tubes. Two explanations for the origin of this accessory cervix are offered: (1) that it originated from a fusion failure of the lower portions of the müllerian ducts, and (2) that it arose from the urogenital sinus.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90022-9

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractA case is described in which aminocentesis caused placental injury, abruptic placenta, and fetal hemorrhage which caused fetal distress. This was primarily manifested by reduction of fetal movements and later by fetal heart rate deceleration. Emergency cesarean section was performed and a live infant was born. The importance of monitoring the fetus after amniocentesis by assessment of fetal movements is stressed.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90023-0

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractTwelve patients with clinical features of pseudocyesis were divided into two groups according to the presence or absence of galactorrhea. The mean serum prolactin level of patients with galactorrhea was significantly higher than the normal values of the patients without galactorrhea. The mean serum levels of luteinizing hormone and follicle‐stimulating hormone were markedly elevated in patients without galactorrhea. This was especially true of luteinizing hormone. Serum levels of human chorionic gonadotropin were undetectable in all patients. The significance of these observations is discussed.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90024-2

出版商:Wiley    

年代:2004

数据来源: WILEY

摘要:

AbstractFive hundred sixty‐one persons were treated in a comprehensive cholera unit during the 1979–1980 cholera outbreak at Ile‐Ife. Sixty‐one pregnant cholera patients were identified and followed up. Compared to the general female population, all female cholera patients in the 15–29 year age group show significantly more resistance to the disease than those aged 30 years and above. The pregnant cases, as well as all reproductive‐years age groups, showed significantly less mortality than both the non‐pregnant patients and those at both extremes of age. Our findings show that pregnancy does not render the woman more susceptible and may, in fact, render her less susceptible after the first trimester, when prognosis brightens for both the mother and the fetus.

ISSN:0020-6695    

DOI:10.1016/0020-7292(81)90025-4

出版商:Wiley    

年代:2004

数据来源: WILEY