ISSN:1059-910X    

DOI:10.1002/jemt.1070260102

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

摘要:

AbstractTo demonstrate by SEM the topography and cytoarchitecture of the different parenchymal components of human salivary glands, we have employed a number of techniques that allow either the exposure of internal and lateral cell surfaces or, following the removal of connective tissue, the visualization of endpieces, ducts, and myoepithelial cells.Serous glands consist of indented acini attached to the ducts in a grape‐like fashion, whereas mucous and mixed glands are made up of smooth tubuli. Myoepithelial cells (mecs), which are abundant on the surfaces of acini, tubuli, and intercalated ducts, are sparse on striated ducts. They are star‐shaped on acini, striated ducts, and most of the tubuli. Spindle‐shaped mecs are seen, instead, on intercalated ducts and, occasionally, on mucous and mixed tubuli as well.Cells of striated ducts split into a number of large basal portions whose surface is covered by long laminated processes responsible for the striations seen with TEM. Excretory ducts are lined by small cup‐shaped basal cells and by tall cylindrical cells, which are completely covered by short processes oriented at random. When observed from below, after removal of the basal lamina, the basal surfaces of cells of excretory ducts exhibit polygonal areas delimited by short reliefs. Those of striated ducts show, instead, long laminar processes arranged radially.Results presented here are discussed and put in relationship to the mechanism of saliva production. © 1993 Wiley

ISSN:1059-910X    

DOI:10.1002/jemt.1070260103

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

ISSN:1059-910X    

DOI:10.1002/jemt.1070260104

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

ISSN:1059-910X    

DOI:10.1002/jemt.1070260105

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

ISSN:1059-910X    

DOI:10.1002/jemt.1070260106

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

ISSN:1059-910X    

DOI:10.1002/jemt.1070260107

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

摘要:

AbstractSalivary secretion is nerve mediated. The salivary glands are supplied by parasympathetic and sympathetic efferent nerves which travel to the glands by separate routes. Once in the glands the axons from each type of nerve intermingle and travel together in association with Schwann cells, forming Schwann‐axon bundles. Two types of neuro‐effector relationships exist with salivary parenchymal and myoepithelial cells:epilemmal(outside the parenchymal basement membrane) andhypolemmal(within the parenchymal basement membrane). Their relative frequencies with either type of nerve differ greatly between glands and species. Salivary blood vessels receive epilemmal innervations by both sympathetic and parasympathetic axons. The classical transmitters—acetylcholine in parasympathetic and noradrenaline in sympathetic axons—are stored in small vesicles. A variety of non‐conventional neuropeptide transmitters have also been found in salivary nerves by immunohistochemistry, and they occur in large dense‐cored vesicles. Prolonged high frequency stimulation has been found to cause depletion of large dense‐cored vesicles from glandular nerves. In recent years afferent nerves have started to be identified and are found in greatest numbers around the main salivary ducts, where they may form a hypolemmal association with the epithelial cells. Functional studies demonstrate complex interactions between parasympathetic and sympathetic nerves. Morphological assessments of changes in the parenchymal cells after nerve stimulations or denervations add greatly to our understanding of the nerve functions. At least four types of influence can be exerted on salivary parenchymal cells by the nerves:hydrokinetic(water mobilizing),proteokinetic(protein secreting),synthetic(inducing synthesis), andtrophic(maintaining normal functional size and state). In respect to each role, wide glandular and species differences exist between the relative contributions made by each type of nerve. © 1993 W

ISSN:1059-910X    

DOI:10.1002/jemt.1070260108

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

ISSN:1059-910X    

DOI:10.1002/jemt.1070260109

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY

ISSN:1059-910X    

DOI:10.1002/jemt.1070260101

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1993

数据来源: WILEY