ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01348.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummaryBlood‐group frequencies in 275 Jews from Cochin, India, are reported. The results are compared with findings in other Jewish communitie

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01349.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummaryThe blood‐group frequencies ofABO, MNandRhin 129 Kurdistan! Jews and 162 Jews from Baghdad are reported.We are indebted to Dr Muhsam, Lecturer in Statistics, the Hebrew University, Jerusalem, for statistical analysis of the dat

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01350.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummaryBlood‐group frequencies in 200 Jews from Tripolitania are reported. The results of the study are compared with findings in other Jewish oriental communitie

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01351.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummaryThere is a significant positive correlation between the birth weights of maternal first cousins, but not between other first cousins. This is interpreted as evidence for the existence of a maternal genetic factor in the determination of birth weight. Using estimates of the correlation between birth weight in sibs, twins and first cousins, the contribution to the total variance in birth weight of such factors as foetal genotype, maternal genotype and environment are discussed.

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01352.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummaryStudies of the electrophoretic haemoglobin patterns in inbred strains of mice have shown two different types of patterns. In three strains, all mice tested had one type of pattern; in five, another type of pattern was found in all animals tested; and in three strains, individual mice showed either one or the other haemoglobin pattern. These data strongly indicate a genetic basis of haemoglobin differences in mice. Further work is needed to determine the exact nature of this genetic basis.

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01353.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummaryA method of estimating the probability of dizygotic and monozygotic twin pairs is described. Parent‐child and sib‐sib frequency tables for theABO, MNSand Rhesus blood‐group systems and formulae for obtaining these tables for theP, Lutheran, Kell, Duffy, Kidd and non‐secretor (or Lewis) systems are given.Tables of the distribution of differences in total finger ridge count andatdpalmar angles are also given.The probability that a given twin pair is monozygotic is estimated in two worked e

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01354.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

Summary1. A technique of estimating thresholds of taste for phenylthiocarbamide intended for use subsequently with small groups of primitively living subjects, has been employed in the first instance in a study of four samples, each of fifty subjects drawn from a civilized ethnic group living in Malaya, the groups being Chinese, European, Indian (Tamil) and Malay.2. The threshold values (recorded as T.S.N. values, viz. as values ofnin the expression, 2–60 × 2‐ng./I., for the threshold concentrations of the substance) have been corrected for age and sex effects to the 32‐year‐old male as standard subject, on the basis of certain assumptions. The corrected data have been found to yield frequency distributions preferable to those yielded by data not so corrected.3. The so‐called ‘non‐taster’: ‘taster’ ratios found in the four samples previously mentioned were 0–02:0‐98, 0–196:0‐804, 0–272:0‐728 and 0–156:0‐844 respectively. As estimates of the ratios in the corresponding ethnic groups, these values have large standard deviations because of the small sample sizes. Even so, the differences between the ratios of the Chinese on the one hand and of each of the other groups on the other, are of appreciable statistical significance. Differences of appreciable statistical significance have been found between the mean T.S.N. values of some of the ‘taster’ fractions (range of means, 9–57‐10‐85) and also between the variances of the T.S.N. values of some of the ‘taster’ fractions (range of variances, 2–512‐6‐937). The findings of the study have been compared with those of some other

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01355.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummarySix human families exhibiting the nail‐patella syndrome have been studied to test for linkage between the nail‐patella locus and the loci of theABO, MNS, Rhesu3,P, Lewis, Kell, Lutheran and Duffy blood groups. Five of these families have contributed information, and alinkagebetween theABOand nail‐patella loci has been demonstrated with a significance level of 1 in 6 × 108. The possibility ofassociationbetween oneABOblood group and the nail‐patella syndrome has been excluded. The recombination value, if homogeneity is assumed, is 10‐4%± 3‐2 % by the maximum likelihood method, and the question of homogeneity has been discussed. No linkage has been demonstrated with the other blood‐group loci, nor is there any evidence of partial sex linkage.The full details of the families have been placed in the archives of the Ga

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01356.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY

摘要:

SummaryThe rate of progress towards homozygosity is calculated for various selection pressures against homozygosity at a given locus, when systematic inbreeding is carried out by selfing, sib mating, half‐sib mating in which a male is mated to two of his half‐sisters who are full sisters, and double first‐cousin mating, under the condition that selection is only allowed to act within lines, i.e. there is no tendency to replace more homozygous by less homozygous lines because of the greater fertility, etc., of the latter.The systems of inbreeding considered require respectively 1, 2, 3 and 4 parents per generation per line. If the homozygotesaaandbbboth have survival values, compared with 1 forah, then for all finiteahomozygosity is eventually achieved, but as a is reduced there is a greater relative slowing down of progress in the milder than in the more intense forms of inbreeding, e.g. whensis reduced from 1 to 0–2 the number of generations required to make a given amount of progress is multiplied by 3–8 for selfing, by 14 for sib mating, by 30 for half‐sib mating, and by 142 for double first‐cousin mating.The solution is also given for various survival values ofaawhenbbis lethal. Makingbblethal instead of equal in fitness toaaspeeds up the rate of progress when the survival value ofaais greater than about 90% for sib mating, 40% for half‐sib mating and 20% for double first‐cousin mating.In the case of sib mating, whenaaandbbhave survival valuess1ands2, then it appears that for any fixed Sj the rate of progress has a minimum for a value of s2less thans1. It is assumed that the same applies to half‐sib and double first‐cousin mating.Taken in conjunction with Hayman&Mather's analysis of the effects of inbreeding when selection against homozygosis occurs between lines as well as within lines, it appears that inbreeding to obtain homozygosity should be carried out so as to minimize selection between lines and also as intensely as possible. The latter conclusion may need qualifying if interaction between homozygous loci causes a large proportion of the possible homozygous geno

ISSN:0003-4800    

DOI:10.1111/j.1469-1809.1955.tb01357.x

出版商:Blackwell Publishing Ltd    

年代:1955

数据来源: WILEY