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11. |
Sensitivity of selected drug biotransformation enzymes to dietary protein levels in adult F344 male rats |
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Journal of Biochemical Toxicology,
Volume 4,
Issue 1,
1989,
Page 71-72
L. E. Butler,
W. C. Dauterman,
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摘要:
AbstractAdult male Fischer 344 rats were fed inadequate, adequate, and excessive quantities of dietary protein (8, 12, and 22%, respectively) for a period of 14 days. An increase in dietary protein did not increase liver weight but resulted in an increase in cytochromeP‐450 content and 7‐ethoxycoumarinO‐deethylase activity. No significant difference in glutathioneS‐transferase activity was observed at the three protein levels. The in vivo hepatotoxicity of bromobenzene increased with an elevation in dietary protein intake from 12 to 22%. These data from mature rats follow trends similar to findings we have reported previously with juveni
ISSN:0887-2082
DOI:10.1002/jbt.2570040112
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1989
数据来源: WILEY
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12. |
Masthead |
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Journal of Biochemical Toxicology,
Volume 4,
Issue 1,
1989,
Page -
Preview
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PDF (72KB)
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ISSN:0887-2082
DOI:10.1002/jbt.2570040101
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1989
数据来源: WILEY
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