摘要:

Summary.Phagocytosis by normal human neutrophils and the bactericidal activity of normal human pooled serum were measured under anaerobic conditions on six endodontic pathogenic bacterial species from the generaActmomyces, Bacteroides, Fusobacterium, PeptostreptococcusandStreptococcus. The results revealed thatActinomyces viscosuswas not killed either by human neutrophils or by 20 per cent serum;Peptostreptococcus anaerobiuswas not killed by either 20 per cent or 95 per cent serum; andBacteroides intermediuswas susceptible to both 20 per cent and 95 per cent serum, but was not killed by neutrophils after exposure for 20 minutes. The other species showed intermediate susceptibility patterns. Such results suggest that oral pathogens vary with regard to the bactericidal effects of these two host defence mechanisms, and that this variation may at least in part explain the relative quantities of microbes recovered in certain oral infections.

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00099.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Summary.Three common oral bacteria, namelyStreptococcus sanguis. Actinomyces viscosusandCurynebacteriumspp, were studied with regard to their ability to penetrate etched and unetched dentine and for their effect on underlying cell cultures. The test organisms were grown in cylinders above dentine slices 100 and 500 μm thick for 72 hours. The slices were in contact with tissue culture medium covering a layer of fibroblasts. Penetration of 100 μm slices was most rapid with 5.sanguis, followed byA. viscosusandCorynebacterium. The pattern was similar but slightly delayed when 500 μm slices were used, but in most cases penetration had occurred by 72 hours. The presence of a smear layer had no effect on the results obtained. Following penetration, cell destruction was most extensive withS. sanguis, the most cytotoxic organism, followed byCorynebacteriumandA. viscosus. In the limited number of dishes where no penetration occurred there was little effect on cell numbe

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00100.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Summary.Anin vitromethod for the cytotoxicity testing of endodontic materials is described which aims to simulate the clinical situation. Materials can be tested in the presence or absence of a compacted layer of dentine chips mimicking the periapical dentine plug. A total of twelve materials were tested. In the absence of dentine, Kloroperka, Biocalex, Diaket and Endomethasone were slightly cytotoxic; AH26 with and without silver, Sealapex, Tubliseal and Kerr's pulp canal sealer were moderately cytotoxic, while Forfenan, Spad and Kri paste were strongly cytotoxic. In the presence of dentine the cytotoxicity of these materials was considerably reduced, with the exception of Endomethasone, Forfenan, Spad and Kri paste. The method provides a satisfactory alternative to implantation testing and is an inexpensive and reproducible test system in which dentine can be incorporated.

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00101.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Summary.A study of the subcutaneous connective tissue response of 24 white rats to three different formulations of gutta‐percha was undertaken. The prepared specimens were examined under the light microscope after intervals of 7, 21, 60 and 120 days.The results showed identical tissue responses after the initial period of 7days. However, after 120 days the gutta‐percha supplied with the Ultrafil system presented mature granulation tissue with neither oedema nor vascular congestion, in contrast to the responses observed with the McSpadden and Obtura formulati

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00102.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Book review in this article:O. Clast and the Bros. BlastF. M. Andreasen.

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00103.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00104.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00105.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00106.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0143-2885    

DOI:10.1111/j.1365-2591.1990.tb00107.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY