摘要:

AbstractCytokines are believed to play an important role in the pathogenesis of periodontal diseases. In the present study, gingival crevicular fluid (GCF) levels of two important cytokines, interleukin 1‐/3 (IL‐1β) and tumour necrosis factor‐α (TNF‐α) and, in addition, serum IL‐1β levels, were determined in patients with severe and rapid periodontal breakdown by use of ELISA. While IL‐1β was detected in all of the GCF samples studied, TNF‐α could only be detected in about half the samples. The mean GCF IL‐1β level was 38.45 ± 13.99 pg/mL, and the mean TNF‐α level was 3.20 ± 1.39 pg/mL, respectively. The GCF IL‐1β levels also presented a strong positive correlation with the mean pocket depths. Although weak, both of the cytokines also presented correlations with the presence of bleeding on probing. Additionally GCF samples contained increased IL‐1β levels when compared with the serum samples suggesting local production mechanisms. The findings of the present study suggest that these cytokines may be involved in the pathogenesis of periodontal diseases (IL‐1β being more significant), and also may help in defining the a

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05614.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

AbstractAppropriate methods of assessing the cutting ability of handpiece and rotary cutting instrument combinations are needed for research into the processes involved in dental cutting. They are also required for the development of improved devices and recommendations on operation as well as for equipment specification and standards testing.In reviewing the literature on dental rotary cutting performance testing to evaluate available methods, the factors which may influence clinical cutting behaviour are identified as those related to characteristics of the operator, handpiece, rotary cutting instrument, coolant/lubricant used and workpiece material. Existing industrial cutting theory is of limited help in understanding dental cutting in view of the differences between the control of relevant variables in the two cases. Consideration is given to the ways in which the important variables have (or have not) been controlled in past studies of dental cutting and thus the clinical relevance of available methods evaluated. Serious problems such as the lack of suitable test workpiece materials, as well as deficiencies in current knowledge of operator behaviour, handpiece characteristics and effects of coolant/lubricant application are noted. It is concluded that before improved, clinically relevant tests can be developed, further fundamental research in these areas is essential and that until this is done, further work under arbitrary experimental conditions would be of little value.

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05615.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05616.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05617.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05618.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05619.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

Book reviewed in this article:ANTIBIOTIC GUIDELINES, ANALGESIC GUIDELINES, CARDIOVASCULAR DRUG GUIDELINES: Victorian Drug Usage Advisory CommitteeMANAGEMENT OF THE TEMPOROMANDIBULAR DISORDERS AND OCCLUSION: J.P. OkesonPROBLEMS AND SOLUTIONS IN COMPLETE DENTURE PROSTHODONTICS: D.J. LambWHY REPLACE A MISSING BACK TOOTH?. J.M. Berns, ed.

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05620.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05621.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05622.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0045-0421    

DOI:10.1111/j.1834-7819.1995.tb05623.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY