摘要:

Showing that ethanol added in vitro increased the fluidity of mouse erythrocyte and synaptosomal membranes and that the same membranes Isolated from mice after chronic treatment with ethanol had increased cholesterol and were resistant to ethanol in vitro, the study suggests that the animals had adapted to the chronic presence of the drug by changing their membrane lipid composition to offset the fluidizing effects of ethanol.

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04767.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Mammalian cells may retain a limited capacity to alter membrane phospholipid fatty acid composition. This may play a role in adaptation to the presence of ethanol (cellular tolerance) and in the response to the removal of ethanol and the withdrawal syndrome.

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04768.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Reporting an unexpected finding, this article suggests a bidirectional cross‐tolerance between ethanol‐tolerant and temperature‐adapted preparations may be a widespread phenomenon. Further investigation of these findings may provide useful insight into the nature of the specific membrane changes in alcohol tole

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04769.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Using fluorescence techniques to study changes in membrane structure as a function of ethanol concentration and alcoholism, it was found that ethanol primarily affects probes located at the membrane‐water Interface. Changes in the lipid composition of membranes during alcoholism were detected by fluorescent probes that partition into the hydrophobic interior of the membran

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04770.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Enzyme markers associated with calcium and glycoprotein metabolism may be correlated with the sensitivity and preference to alcohol in rodent strains.

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04771.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

An index of developmental level of functioning, derived from the Rorschach, was compared with several other prognostic measures to predict treatment outcome.

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04772.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Rats chronically led ethanol developed liver injury only if they also received low doses of the alcohol dehydrogenase inhibitor, 4‐methylpyrazole, suggesting that the consistency of the influence of ethanol and its metabolism, rather than the level of acetaldehyde or the degree of the metabolic effects, contributes to the pathogenesis of alcoholic liver damag

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04773.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

With the acceptance of alcoholism as a disease, many previously obscure ailments are being recognized, among them, central pontine myelinolysis. This case report reviews the diagnostic criteria and methods used in reversing the usual morbid outcome.

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04774.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Book reviewed in this article:Anderson DJ, Kammeier ML,* Holmes HL: Applied Research: Impact on Decision Making.Kammeier ML,* Laundergan JC: The Outcome of Treatment: Patients Admitted to Hazelden in 1975.Hornik EL: The Drinking Woman. New York, Association Press, 1977.

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04775.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0145-6008    

DOI:10.1111/j.1530-0277.1979.tb04777.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY