ISSN:0265-9247    

DOI:10.1002/bies.950010602

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractThe Z‐conformation, recently elucidated in crystals of synthetic alternating dG‐dC polymers, is a dramatically different structure for DNA. Despite suggestive locations of alternating purine‐pyrimidine tracts in chromosomes and intriguing functional hypotheses, unequivocal demonstrations of the Z‐conformation in vivo are not proving easy. Perhaps the Z‐conformation should be considered largely as a dynamic structure transiently forming in torsionally stressed

ISSN:0265-9247    

DOI:10.1002/bies.950010603

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractAll insects appear to have a transport lipoprotein in the hemolymph (blood) that is responsible for moving hydrophobic materials through aqueous compartments. This has been called lipophorin because it is believed to be a reversible transport shuttle. Since most insects undergo some degree of metamorphosis from larval stages to the adult, the need to transport hydrophobic materials or the nature of these materials may change in the course of the life span. This is especially marked in the case of the holometabolous insects – those which undergo drastic change of form, e.g. caterpillar‐pupa‐adult moth. We have found that lipophorin undergoes a molecular metamorphosis paralleling that of the i

ISSN:0265-9247    

DOI:10.1002/bies.950010604

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractOur chromosomes are full of the dead relics of genes. DNA analysis is beginning to unravel the origin and fate of these pseudogenes, and the influence that they may have on genome organization and evolution.

ISSN:0265-9247    

DOI:10.1002/bies.950010605

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractLife is characterized by a selectivity for asymmetric molecules. A great deal of theoretical and experimental work has yet to explain why living organisms utilize only L‐amino acids in proteins and D‐sugars in RNA and DNA. Also unknown is how a form of life based on asymmetric molecules evolved from an environment containing a racemic mixture of prebiotic molecules. By what mechanism did this selectivity for asymmetric molecules take pl

ISSN:0265-9247    

DOI:10.1002/bies.950010606

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractThe molecular components of complement are a major part of the armoury of the mammalian immune system, being required for the lysis of antibody‐targeted cells. Several of the complement proteins are known to be encoded by genes within the major histocompatibility complex (MHC). Molecular analysis of these genes is providing new information on the basis of complement action and the possible roles of this system in autoimmune diseas

ISSN:0265-9247    

DOI:10.1002/bies.950010607

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractEarlier investigations of the hormonal control of vitellogenin (egg‐yolk protein) synthesis in mosquitoes relied on microsurgical manipulations to identify organs that secrete the various hormones that stimulate or inhibit vitellogenesis. Advances in the last 10 years, using radioimmunoassays, HPLC, mass spectrometry and tissue‐culture incubations, have shown that the control mechanism involves a complex interaction between ecdysteroids, juvenile hormones and peptide hormo

ISSN:0265-9247    

DOI:10.1002/bies.950010608

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

ISSN:0265-9247    

DOI:10.1002/bies.950010609

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

摘要:

AbstractThe preparation of samples for gene diagnosis is time‐consuming, labor‐intensive and costly. These problems can be overcome by dissolving a biological source in a strong solution of a chaotropic salt, then filtering the solution through an immobilizing membrane. Conditions exist for causing the selective immobilization of either DNA or mRNA. The resultant membrane is immediately ready for reaction with labeled gene pro

ISSN:0265-9247    

DOI:10.1002/bies.950010610

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY

ISSN:0265-9247    

DOI:10.1002/bies.950010611

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1984

数据来源: WILEY