摘要:

AbstractVarious pyridazin‐3(2H)‐ones, 3‐chloropyridazines and pyridazin‐3(2H)‐thiones were synthesized and treated with the sulpha drug (knowing by sulphamethoxazole). All the new compounds were evaluated for their antibacterial activity. They showed significant antibacterial activity againstStaphylococcus aureusandBacillus subtilis(Gram + ve) andE. coli, Pseudomonas aeruginosaandYersinia enterocolitica(Gram ‐ ve) bacteria by agar plate diffusion method.All proposed structures were confirmed by IR,1H NMR, Mass spectra and Element

ISSN:0009-4536    

DOI:10.1002/jccs.200400143

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractThe enantioselective synthesis of the neolignans Rhaphidecursinol A and Virolongin B is reported for the first time. The key reactions in the synthesis were Sharpless asymmetric dihydroxylation and Mitsunobu reaction. The absolute configuration of Rhaphidecursinol A was confirmed.

ISSN:0009-4536    

DOI:10.1002/jccs.200400144

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractPolysubstituted pyridone derivatives were obtained through interaction of cyanoacetanilides with different reagents such as chalcones, 1,1,3‐tricyano‐2‐aminopropene, and arylidenemalononitrile and acetyl‐

ISSN:0009-4536    

DOI:10.1002/jccs.200400145

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractA convenient synthesis of some novel 6‐amino‐4‐aryl‐1‐phenyl‐3‐pyridin‐4‐yl‐1,4‐dihydropyrano[2,3‐c]pyrazole‐5‐carbonitriles (3a,b) and 5‐chloro‐1‐phenyl‐3‐pyridin‐4‐yl‐1H‐pyrazole‐4‐carbaldehyde (4) is described. Compound4was obtained by the reaction of 2‐phenyl‐5‐pyridin‐4‐yl‐2,4‐dihydropyrazol‐3‐one (1) with dimethylformamide and phosphorus oxychloride under Vilsmeier‐Haack reaction conditions. Compound4was subjected to react with different reagents such as hippuric acid, sodium azide and aromatic ketones to afford 4‐(5‐chloro‐1‐phenyl‐3‐pyridin‐4‐yl‐1H‐pyrazolo‐4‐ylmethylene)‐2‐phenyl‐4H‐oxazol‐5‐one (5), 5‐azido‐1‐phenyl‐3‐pyridin‐4‐yl‐1H‐pyrazol‐4‐carbaldehyde (8) and 1‐aryl‐3‐(5‐chloro‐1‐phenyl‐3‐pyridin‐4‐yl‐1H‐pyrazol‐4

ISSN:0009-4536    

DOI:10.1002/jccs.200400146

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractThe samples of Red Palm Oil (RPO) were irradiated with gamma rays using a Cobalt‐60 source (ISSLEDOVATEL, CIS), to dose levels of 1, 5, 10, 15 and 20 KGy and kept for the storage period of 8 weeks along with an untreated control at ambient conditions. The samples were tested for physical characteristics, i.e., Peroxide Value (POV), Iodine Value (IV), Free Fatty Acid value (FFA), Anisidine Value (AV), Color and β‐Carotene. Results revealed that the POV, FFA, and AV were higher in the irradiated samples than the control at the completion of the experimental period. It was also observed that these effects were positively correlated with increasing the irradiation dose. However, a reversed trend was noted in the case of Iodine Value, color and β‐C

ISSN:0009-4536    

DOI:10.1002/jccs.200400147

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractAn efficient and convenient solid state reaction using Fe(NO3)3·9H2O/NaHSO4·H2O to oxidize aryl‐substituted semicarbazides for preparing azo compounds has been reported. EightN‐aryl‐2‐phenyldiazenecarboxamides have been synthesized in excellent yields at room temperature. The method is efficient

ISSN:0009-4536    

DOI:10.1002/jccs.200400148

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

Abstract(±)‐Eusiderin E, (±)‐Eusiderin F, (±)‐Eusiderin K, (±)‐Eusiderin J, (±)‐Eusiderin M and (±)‐Eusiderin G were first synthesized from pyrogallol, in which the Claisen Rearrangement was used to afford two imp

ISSN:0009-4536    

DOI:10.1002/jccs.200400149

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractThe reactions of free radical addition to allylic compounds are believed to proceed the SH2′ mechanism. It is not clear whether the SH2′ mechanism is concerted or stepwise. The leaving group effects and the secondary α‐deuterium kinetic isotope effects in free radical SH2′ reactions have been determined. The leaving group effect, kBr/kCl, is from 1.88 to 14.3. The secondary α‐deuterium kinetic isotope effects, kH/kD, are 1.20 for 2‐methylallyl chloride and 1,1‐d2‐2‐methylallyl chloride and 1.22 for allyl chloride and 1,1‐d2‐allyl chloride. The free radical SH2′ reactions seem to favo

ISSN:0009-4536    

DOI:10.1002/jccs.200400150

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractA series ofN‐(5‐aryl‐2‐furoyl)thiourea derivatives containing substituted pyrimidine ring were synthesized in good yield using PEG‐400 as solid‐liquid phase transfer catalyst under ultrasonic irradiation. The structures of all newly synthesized compounds were elucidated and confirmed by IR,1H NMR and elemental analysis. Our method has the advantage of shorter reaction time and higher reaction yield compared to the conventional heating method. Preliminary biological tests show that some of the target compounds have better inhibitory activities against roots and stalks of monocotyledon and dicotyl

ISSN:0009-4536    

DOI:10.1002/jccs.200400151

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY

摘要:

AbstractA new and concise method for the synthesis of angelicin was described. 7‐Hydroxycoumarin was converted into angelicin in good overall yieldsviathe process ofc‐propenation‐o‐vinylation and ring‐closing metathe

ISSN:0009-4536    

DOI:10.1002/jccs.200400152

出版商:WILEY‐VCH Verlag    

年代:2004

数据来源: WILEY