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| 11. |
Role of interferon alpha‐2a in the treatment of polycythemia vera |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 55-57
Paolo Foa,
Paolo Massaro,
Sonia Ribera,
Alessandra Lurlo,
Carmen Mezzanotte,
Daniela Giandalia,
Anna Teresa Maiolo,
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摘要:
AbstractWe studied the effects of recombinant interferon alpha‐2a (IFN‐alpha) in 36 patients with polycythemia vera (PV) previously treated with phlebotomy and/or conventional cytostatic agents. In each patient, after at least 2 months of discontinuation of any cytotoxic therapy, the hematocrit (Hmt) was first brought to normal value by phlebotomy; IFN‐alpha treatment was then begun at a starting dose of 3,000,000 IU s. c. three times a week. Response to treatment, which was assessed monthly, was defined as persistent normalization of Hmt without concomitant phlebotomy; in non‐responsive patients the initial IFN‐alpha weekly dosage was progressively increased. Twenty patients were responsive with a median duration of response of 7 months (range 2‐25+ months); out of these, 7 patients are still under treatment and responsive at 13+, 17+, 20+, 22+, 23+, 25+, 25+ months. These findings indicate that a cohort, although small, of patients with PV (19.4%) are persistently sensitive to IFN‐alpha; in this subset of patients, this cytokine can therefore provide a useful treatment option, since, contrary to conventional therapeutic approaches such as radioactive phosphorus, cytostatic agents, or phlebotomy, IFN‐alpha is devoid of harmful side effects. ©1995
ISSN:0361-8609
DOI:10.1002/ajh.2830480112
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 12. |
Thrombocytosis: Misdiagnosis and its prevention |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 58-70
Tikva Yermiahu,
Hana Shalev,
Lev Hatskelzon,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480113
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 13. |
Chronic lymphocytic leukemia with localized extranodal prolymphocytic transformation |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 60-62
Dhruv Kumar,
Shimareet Kumar,
Joel D. Bessman,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480116
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 14. |
Cyclic thrombocytopenia successfully treated with low dose hormonal contraception |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 62-63
Carsten Helleberg,
Ellen Taaning,
Per Boye Hansen,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480117
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 15. |
Interstitial 9q‐ and dyserythropoiesis in acute myeloid leukemia |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 63-64
Y. L. Kwong,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480118
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 16. |
Herpes simplex meningoencephalitis simulating meningeal myelomatosis |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 64-65
Lev Shvidel,
Mordechai Shtalrid,
Orit Soffer,
Alain Berrebi,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480119
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 17. |
Anticardiolipin antibodies, functional protein S deficiency, and fetal loss |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 65-66
A. Ruffatti,
L. Dilenardo,
P. Simioni,
S. Tonetto,
A. Girolami,
P. Grella,
S. Todesco,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480120
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 18. |
Multiple myeloma presenting as a manubrial mass with intracytoplasmic crystal accumulation within macrophages |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 66-67
T. E. Towheed,
R. Ferrari,
W. E. N. Corbett,
T. P. Anastassiades,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480121
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 19. |
Constitutional trisomy 8 mosaicism evolving to primary myelodysplastic syndrome: A new subset of biologically related patients? |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 67-68
R. Mastrangelo,
A. Tornesello,
S. Mastrangelo,
M. Zollino,
G. Neri,
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ISSN:0361-8609
DOI:10.1002/ajh.2830480122
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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| 20. |
Does Higher Monocyte Count Predict Increased Alcohol Consumption? |
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American Journal of Hematology,
Volume 48,
Issue 1,
1995,
Page 68-69
J. C. Charvat,
M. H. Brutsche,
R. Imoberdorf,
A. Nanzer,
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PDF (204KB)
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ISSN:0361-8609
DOI:10.1002/ajh.2830480123
出版商:Wiley Subscription Services, Inc., A Wiley Company
年代:1995
数据来源: WILEY
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