摘要:

The variants of the Capgras syndrome can be organized into a structure, the delusion of substitution, which itself is embedded in other structures.

ISSN:0254-4962    

DOI:10.1159/000284875

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

A presentation is given of a long-term personal follow-up investigation of patients with paranoid psychoses consecutively admitted at the University Psychiatric Department in Oslo. The patients were followed-up for the first time after a period of 5–18 years, and again after 22–39 years. On the basis of the findings, it is suggested that the diagnostic category will best indicate the course and outcome for cases with delusional misidentification syndromes.

ISSN:0254-4962    

DOI:10.1159/000284876

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

A delusion can only be ‘explained’ if it can be correlated with a demonstrable brain event, and this is only beginning to be possible. The misidentification syndromes are leading the way in demonstrating a close relationship between quite specific brain abnormalities and highly characteristic delusional symptoms. Although delusional disorder (DSM-IV 297.10) and its treatment are well described, virtually no investigations have been carried out on the neuropathological substrate. This article suggests that delusional disorder is a naturally occurring ‘model psychosis’ which would reward experimental study.

ISSN:0254-4962    

DOI:10.1159/000284877

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

Schizophrenia is associated with structural changes in the brain but it is not clear whether the changes are localized. Studies in Manchester and elsewhere have reported abnormalities in biochemical markers of glutamate- and GABA-containing neurones in post-mortem brains from schizophrenic patients. The abnormalities occur in the ventral frontal cortex and anterior temporal lobe. It is suggested that these regions of the brain specifically encode information about social communication – language, gesture and facial expression. Many of the symptoms of schizophrenia become neuropsychologically understandable when seen as disturbances of social communication. In this and the following papers, experimental tests of this hypothesis are described.

ISSN:0254-4962    

DOI:10.1159/000284878

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

Two experiments are described in which the performance of schizophrenic subjects was investigated, using tests of affect judgement and recognition memory for faces (Warrington), words, and semi-abstract patterns. Schizophrenic subjects were impaired in their ability to describe the emotional states portrayed by actors and presented on video and were more likely to comment on the physical description of the actor or to fail to comment on the emotion at all. Performance on the Warrington Recognition Memory Test for faces suggests a marked impairment in schizophrenia, although impaired performance on recognition memory tests for words and patterns indicates that this abnormality may not be specific for faces.

ISSN:0254-4962    

DOI:10.1159/000284879

出版商:S. Karger AG    

年代:1994

数据来源: Karger

摘要:

Twenty-three schizophrenic subjects and 19 controls completed selected neuropsychological tests of frontal and temporal lobe function and a subgroup of subjects completed a series of tests to assess receptive and expressive aspects of social communication. This was to examine the relationship between deficits of receptive social communication and deficits of temporal lobe function, and deficits of expressive social communication and deficits of frontal lobe function. Schizophrenic subjects were significantly impaired compared to normal control subjects on measures of social communication. Normal performance on a word recognition task contrasted with impaired performance on a face recognition task. No clear pattern of relationships between neuropsychological tests of regional brain function and receptive or expressive social communication emerged. A stepwise logistic regression analysis generated three factors which discriminated between the two groups of subjects; two of these factors were measures involving the information conveyed in a human face.

ISSN:0254-4962    

DOI:10.1159/000284880

出版商:S. Karger AG    

年代:1994

数据来源: Karger

ISSN:0254-4962    

DOI:10.1159/000284881

出版商:S. Karger AG    

年代:1994

数据来源: Karger