摘要:

Neurophysiological investigations – including sensory-evoked responses, contingent negative variation (CNV), and nerve conduction velocities – were done in 11 male polygonosomic patients and in comparison with a control group. Some significant data are reported pointing out differences which may be related to a hypovigil type (47, XYY) and a hypervigil type (47, XXY). The importance of the CNV and conduction velocity as an index of a constitutional minimal brain dysfunction is discus

ISSN:0302-282X    

DOI:10.1159/000117647

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

Excretion of lithium in urine was studied in 2 healthy males while recumbent and while upright, either walking or standing quietly. An oral dose of 24.3 mmol of Li+ was taken as three lithium carbonate tablets 13 h before clearance tests. Renal lithium clearance decreased and lithium fractional reabsorption increased while upright. Standing immersed to the neck in water, which prevents the fall in plasma volume upon changing posture from recumbent to upright, prevented the fall in renal lithium clearance as well as the rise in lithium fractional reabsorption while upright. Oral doses of guanethidine (total dose of 200 mg) or oxprenolol (total dose of 140 mg) taken to prevent high levels of sympathetic nervous system activity and plasma renin, respectively, failed to prevent the fall in renal lithium clearance or the rise in lithium fractional reabsorption upon changing posture from recumbent to upright. The findings indicate that the fall in renal lithium clearance and the rise in lithium fractional reabsorption upon changing posture from recumbent to upright is related to the fall in plasma volume but not to high levels of sympathetic nervous system activity or plasma renin activity.

ISSN:0302-282X    

DOI:10.1159/000117648

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

A chart review study of 86 females with pure depressive disorder (i.e., a diagnosis of depression plus a parental history of depression) is reported. Findings regarding family history of depressive illness are described. Clinically, the group is noted to be most homogeneous, various attempts at subdivision failing.

ISSN:0302-282X    

DOI:10.1159/000117649

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

HLA phenotype distribution was investigated in 91 affective patients. Significant increases over those of the control population were found in HLA-A 29 and in Bw 22 frequencies, while A 10 and A 30 were decreased. No significant difference was shown between the two clinical subgroups (41 unipolar patients and 50 bipolar ones). On comparing our data with those from other authors, Bw 16 was significantly increased. However, a high degree of heterogeneity was also shown for this antigen. Of some interest is the finding that relapsed and non-relapsed patients during long-term lithium therapy display diverging HLA phenotype distributions, with B 5 increased among the non-relapsed subjects.

ISSN:0302-282X    

DOI:10.1159/000117650

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

A psychotic woman with Capgras symptoms is presented in whom evidence of cerebral dysfunction is documented both by neuropsychological and neurophysiological findings. The possible etiological aspects of these symptoms are discussed. The main conclusion arrived at is that Capgras symptoms cannot be explained either on the basis of cerebral dysfunction alone or on the basis of a psychosis alone. The simultaneous presence of cerebral dysfunction and psychosis is necessary for the development of symptoms.

ISSN:0302-282X    

DOI:10.1159/000117651

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

39 chronic schizophrenic out-patients were given either fluphenazine decanoate or enanthate for a 1-year double-blind trial. Doses of 25 mg were given for the first 6 months and 37.5 mg for the last 6 months. For both agents the intervals between treatments lengthened significantly over the course of the trial. Fluphenazine decanoate showed a non-significant trend for a longer duration of action coupled with a significantly lower incidence of extrapyramidal side effects.

ISSN:0302-282X    

DOI:10.1159/000117652

出版商:S. Karger AG    

年代:1978

数据来源: Karger

摘要:

47’, XYYs represent a high percentage of patients admitted in security settings for aggressiveness. By using a polygraphic technique and amine metabolite estimation in the cerebrospinal fluid (CSF), an attempt was made to evaluate the functional activity of the central aminergic system of these patients. No drastic change was observed in sleep patterns of XYYs. The estimation of CSF amine metabolites revealed a normal value for homovanillic acid, but a significant decrease of 5-hydroxyindoleacetic acid turnove

ISSN:0302-282X    

DOI:10.1159/000117653

出版商:S. Karger AG    

年代:1978

数据来源: Karger

ISSN:0302-282X    

DOI:10.1159/000117654

出版商:S. Karger AG    

年代:1978

数据来源: Karger

ISSN:0302-282X    

DOI:10.1159/000117655

出版商:S. Karger AG    

年代:1978

数据来源: Karger

ISSN:0302-282X    

DOI:10.1159/000117656

出版商:S. Karger AG    

年代:1978

数据来源: Karger