摘要:

Twenty-two female patients with anorexia nervosa, restricted type, 14–35 years old, were treated with a 4-month course of combined cognitive-behavioral therapy, nutritional counselling and antidepressant drugs (nortriptyline for 7, fluoxetine for 15). Patients were monitored for body mass index (BMI), for eating disorder symptoms by the Eating Disorder Inventory (EDI) and the Bulimic Investigation Test (BITE) and for depression and anxiety by the Hamilton Rating Scales for Depression and for Anxiety (HRS-D and -A). The scores were determined before and after 1, 2 and 4 months of therapy. BMI, depression, anxiety and EDI scores improved significantly and equally in both groups during the 4 months of therapy, while BITE scores did not chang

ISSN:0302-282X    

DOI:10.1159/000119213

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

Thirteen women with anorexia nervosa, binge-eating/purging type (AN-BP), 17–43 years old, were treated with a 4-month course of combined cognitive-behavioral, nutritional and antidepressant therapy (7 with amineptine and 6 with fluoxetine). Patients were monitored before and after 1, 2 and 4 months of treatment for body mass index (BMI), for eating disorder symptoms by the Eating Disorder Inventory (EDI) and the Bulimic Investigation Test (BITE) and for depression and anxiety by the Hamilton Rating Scales for Depression and for Anxiety. BMI, EDI scores, depression and anxiety improved significantly and equally in the two groups during the 4 months of therapy, while BITE scores did not chang

ISSN:0302-282X    

DOI:10.1159/000119214

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

Fifteen women with bulimia nervosa were treated with a 4-month course of combined cognitive-behavioral, nutritional and antidepressant therapy (5 with amineptine and 10 with fluvoxamine). Patients were monitored before and after 1, 2 and 4 months of therapy for body mass index (BMI), for eating disorder symptoms by the Eating Disorder Inventory (EDI) and the Bulimic Investigation Test (BITE), and for depression and anxiety by the Hamilton Rating Scale for Depression and for Anxiety (HRS-D and -A). BITE symptoms and gravity improved significantly and equally in the two groups during the 4 months of therapy. Global EDI scores, depression and anxiety decreased, but not significantly. BMI was normal before therapy and did not change during treatment.

ISSN:0302-282X    

DOI:10.1159/000119215

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

In the present study, P3OO has been recorded in 26 subjects (15 women) 1 month after an aggression without organic complications. Among our sample, 16 subjects fulfilled DSM-III-R criteria for posttraumatic stress disorder (PTSD) and 10 did not. P3OO amplitude was significantly lower in the 16 PTSD subjects as compared to the 10 subjects without PTSD. This study supports information processing disturbances in PTSD.

ISSN:0302-282X    

DOI:10.1159/000119216

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

Twenty-one medication-free patients with generalized anxiety disorder (GAD) collected urine samples for 5-hydroxyindoleacetic acid (5-HIAA) and N-acetyl-β-glucosaminidase (NAG). Nine patients with no comorbid psychiatric diagnosis showed a significant association between 5-HIAA and NAG, r = –0.683, p = 0.04. The possibility that NAG could be a marker for serotonin metabolism is discuss

ISSN:0302-282X    

DOI:10.1159/000119217

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

A British author has put forward a new explanation for Joan of Arc’s behaviour. This author suggests that the voices Joan of Arc heard were due to the presence of a temporal lobe tuberculoma in the context of widespread chronic tuberculosis (exposure to bovine tuberculosis, amenorrhoea, heart and intestines incombustible). We consider that some elements are incompatible with widespread tuberculosis. It is difficult to draw final conclusions, but it would seem unlikely that widespread tuberculosis, a serious disease, was present in this ‘patient’ whose life-style and activities would surely have been impossible had such a serious disease been pr

ISSN:0302-282X    

DOI:10.1159/000119218

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

In a double-blind placebo-controlled psychopharmacological study 263 patients with cognitive impairment were screened and 137 of them were selected (following defined inclusion and exclusion criteria) to participate in a clinical trial (for results of treatment phase see part II, in preparation). The pretreatment state was evaluated twice using quantitative-topological EEG (qEEG) and psychopathological rating scales. There is a significant correlation between total score values of nearly all dementia-specific neuropsychological rating scales and absolute spectral power in the lower frequency ranges (delta, theta, alphas at rest. In order to increase the diagnostic power, qEEG was recorded simultaneously with the performance in four different psychometric tests. It was found that the worse the psychopathological rating of a patient, the higher the absolute theta power at rest and the smaller the test- and demand-dependent further increase in theta power. The percentage of task-induced power increase in delta and theta frequency range appeared to be an efficient indicator for a reliable discrimination between healthy elderly individuals and demented patients (rank correlation coefficient for theta in F7: r = +0.55), which will also serve for evaluation of treatment.

ISSN:0302-282X    

DOI:10.1159/000119219

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

The possibility that the taking of vitamin supplements may influence mood was explored. One hundred and twenty-nine young healthy adults took either 10 times the recommended daily dose of 9 vitamins, or a placebo, under a double-blind procedure, for a year. Males taking the vitamins differed from those taking the placebo in that they reported themselves as feeling more ‘agreeable’ after 12 months. After 12 months the mood of females taking the vitamin supplement was significantly improved in that they felt more ‘agreeable’, more composed and reported better mental health. These changes in mood after a year occurred even though the blood status of 9 vitamins reached a plateau after 3 months: this improvement in mood was associated in particular with improved ribofiavin and pyridoxine status. In females baseline thiamin status was associated with poor mood and an improvement in thiamin status after 3 months was associated with improv

ISSN:0302-282X    

DOI:10.1159/000119220

出版商:S. Karger AG    

年代:1995

数据来源: Karger

摘要:

Quantitative EEG is a sensitive method used to assess the effects of pharmacological substances on the central nervous system (CNS) activity. A standard technique is to measure the EEG under vigilance-controlled and resting conditions for a short duration, for example 5 min. The aim of the present study was to investigate the stability of 5-min EEG recordings. While the time course of the EEG was fairly stable during the recording session under the vigilance-controlled condition, systematic trends became apparent under the resting condition. Pharmaco-sensitivity of the EEG and its reliability increased with the recording duration. Five minutes of EEG recording seem to be sufficient and well chosen to evaluate the influence of drugs on the EEG.

ISSN:0302-282X    

DOI:10.1159/000119221

出版商:S. Karger AG    

年代:1995

数据来源: Karger