|
31. |
Anin VitroAnimal Model for the Study of Cereal Components Toxic in Celiac Disease |
|
Pediatric Research,
Volume 18,
Issue 12,
1984,
Page 1372-1378
S AURICCHIO,
M CARDELLI,
G DE RITIS,
M DE VINCENZI,
F LATTE,
V SILANO,
Preview
|
PDF (761KB)
|
|
摘要:
Peptic-tryptic-Cotazym (PTC) digests were obtained, simulatingin vivoprotein digestion, from rice, maize, rye, oats, barley, and sorghum prolamines and tested on small intestine cultures from rat fetus. The PTC digests of the prolamine fractions from rice and maize, even when tested at a concentration as high as 0.5 mg/ml, did not affectin vitrodifferentiation and maturation of fetal rat jejunum that took placein vitroin a way comparable to what happens in vivo. On the contrary, the PTC digests of prolamines from rye, oats, barley, and sorghum were very active in slowing down in vitro development of fetal rat intestine. These results further strengthen earlier findings and all together show that there is a strong correlation between toxicity results of cereal and/or cereal components assessed with clinical trials orin vitrosystems based on bioptic specimens of intestinal mucosa from celiac patients and with the culture of rat fetal intestine. Therefore, the rat fetal intestine culture is considered to be an adequate model for screening and investigating cereal peptides which are toxic for the celiac small intestinal mucosa.
ISSN:0031-3998
出版商:OVID
年代:1984
数据来源: OVID
|
32. |
The Compleat Pediatrician: Howland Awardee Henry Lewis Barnett |
|
Pediatric Research,
Volume 18,
Issue 12,
1984,
Page 1379-1383
NORMAN KRETCHMER,
Preview
|
PDF (557KB)
|
|
ISSN:0031-3998
出版商:OVID
年代:1984
数据来源: OVID
|
33. |
Acceptance of the John Howland Medal and Award of the American Pediatric Society for 1984 |
|
Pediatric Research,
Volume 18,
Issue 12,
1984,
Page 1383-1384
HENRY BARNETT,
Preview
|
PDF (202KB)
|
|
ISSN:0031-3998
出版商:OVID
年代:1984
数据来源: OVID
|
34. |
ANNOUNCEMENTS |
|
Pediatric Research,
Volume 18,
Issue 12,
1984,
Page 1385-1385
&NA; &NA;,
Preview
|
PDF (72KB)
|
|
ISSN:0031-3998
出版商:OVID
年代:1984
数据来源: OVID
|
35. |
Author Index to Volume 18 |
|
Pediatric Research,
Volume 18,
Issue 12,
1984,
Page 1386-1389
&NA; &NA;,
Preview
|
PDF (291KB)
|
|
ISSN:0031-3998
出版商:OVID
年代:1984
数据来源: OVID
|
36. |
Subject Index to Volume 18 |
|
Pediatric Research,
Volume 18,
Issue 12,
1984,
Page 1390-1400
&NA; &NA;,
Preview
|
PDF (1266KB)
|
|
ISSN:0031-3998
出版商:OVID
年代:1984
数据来源: OVID
|
|