摘要:

ABSTRACT:Circumscribed dermal hypermelanosis refers to a group of cutaneous disorders with circumscribed blue, blue‐grey, slate‐grey, or blue‐black pigmentation. Dermal Melanocyte deposition (melanocytosis) and melanin in mdcrophages (melaninosis) are observed histopathologically. This group of disorders can be differentiated clinically from brown epidermal hypermelanosis by examination using Wood's light. The microscopic, histochemical, immunofluorescent, and ultrastructural findings in three cases of erythema dyschromicum Persians supports its classification in the group of circumscribed dermal melanosis. Damage to epidermal basal cells gives rise to a caseade of events producing the’ ashen‐gray color. The epidermal melanocytes in this disorder are morphologically distinctive and increased in number. Ultrastructurally, a direct interaction between melanocytes and lymphocytes's seen resulting in vacuolar degeneration of the dermalepidermal junction, with resultant incontinence of pigment. The dermal depth to which the pigment‐containing macro‐phages may extend is greater than that found in post‐inflammatory hyperpigmentation. perhaps because of involvement of the appenda

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00484.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT:A 40‐yeair‐old‐woman with choriocarcinoma expedient ed several episodes of generalized bulimia lesions while undergoing chemotherapy. The lesions were diegnosed clinically as bullous pemphigoid and this was confirmed by histologic examination and direct immunofluorescent studies. The role of immunology factors and chemotherapeutic agents as a possible etiology of bullous pemphigoid is disc

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00485.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00486.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT:A young girl who developed classical insulin‐dependent diabetes mellitus at one year of age also developed carotinemia and a typical picture of juvenile xanthogranuloma beginning at five months of age which exhibited A waxing and waning courses. When her diabetes was well‐controlled, her serum lipid levels were within normal limits. This is the first reported association of diabetes mellitus and juvenile xanthogranuloma, which together with previous reports of eye, cardiac, pulmonary, and posterior pituitary involvement in children with juvenile xanthogranuloma, suggests that the rare organ involvement in this disease, as well as the characteristic skin lesions, could result from similar etiologic factors which still remain to be elucida

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00487.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00488.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00489.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00490.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00491.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00492.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1982.tb00493.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY