ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01277.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01278.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01279.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01280.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

ABSTRACT:Humoral and cellular immunity were evaluated in 10 patients with Darier's disease. The mean levels of serum immunoglobulins, serum complement, peripheral macro‐phages, and peripheral B and T lymphocytes were within normal limits. Secretory IgA was present in all patients studied. Skin tests for delayed hypersensitivity revealed complete anergy in one of the eight patients tested. Lymphocyte transformation tests revealed statistically significant enhanced responsiveness to both PHA and ConA mitogens in several concentrations studied. These findings may suggest either the existence of alterations in immunoregulation of lymphocyte subpopulations in Darier's disease or may be limited to alterations in membrane functions of certain lymphocyte subpopulations which can be detected only in vitro. The role that such immunologic aberrations may play in the pathogenesis of Darier's disease is still obscur

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01281.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

ABSTRACT:Ninety‐two Chinese Canadian newborn infants (49 boys and 43 girls J and 1633 Chinese Canadian children (819 boys and 814 girls J in Calgary, Alberta, Canada were examined for the presence of Mongolian spots. Mongolian spots were present in all newborns and disappeared slowly until 6 years of age when the rate of disappearance increased. At 10 years of age, none were found. The overall incidence regardless of age was 58% in boys and 53.3% in girls. The most frequent site of involvement was the sacrococcygeal area, followed by the gluteal and lumbar areas. Both sides were equally affected. In only 7.8% of boys and 3.3% of girls was the involved area greater than 15% of the body surface area. Most (63.8% of boys and 67.4% of girls J had less than 5% involved. The color of the Mongolian spots varied from gray to grayish blue to grayish black. In general, younger children had darker Mongolian spot

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01282.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01283.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

摘要:

ABSTRACT:Prevalence among leprosy patients of children in the age group of 0–14 years was 3.8%, with 9 male preponderance. The children were largely immigrants from the endemic neighboring states of Uttar Pradesh and Bihar. A borderline group formed the bulk of the patients. The disease had its onset between ages 5 and 9 in more than half the patients. There was a striking contrast between the age at onset and that of reporting. Usually, the lesions were multiple. Single lesions were, however, present on the exposed parts. Skin‐slit‐smears were positive in borderline borderline (BB), borderline lepromatous (BL), and lepromatous lepromatous (LL) only. A good clinicopathologic correlation was apparent in most pat

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01284.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01285.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1988.tb01286.x

出版商:Blackwell Publishing Ltd    

年代:1988

数据来源: WILEY