ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02829.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02830.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02831.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02832.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02833.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

AbstractBackground.Nontuberculous mycobacterial (NTB) infections are not commonly diagnosed in Thailand. The dissertation of reported cases among 10 published reports of 44 cases within 20 years revealed only six cases of cutaneous infections in which M. marinum was not included.Methods.The proven cases of M. marinum infection were studied at the Institute of Dermatology, Bangkok from 1981 to 1990. The clinical data, histopathology, tuberculin test, chest x‐ray, and treatments were recorded.Results.M. marinum skin infection accounted for 18 cases (81.8% of NTB skin infection), 10 men and 8 women. A history of preceding trauma occurred in 11 cases (61.1%), most of which were negligible wounds or minor abrasions. Twelve cases (66.7%) were in contact with organisms in their occupations and hobbies associated with fish and water exposure.Conclusions.Eighteen cases of M. marinum cutaneous infection acquired from occupations and hobbies were reported. The term “M. marinum cutaneous infection” or “M. marinum granuloma” instead of swimming pool granuloma or fish tank granuloma was proposed. According to this study, cotrimoxazole was the most appropriate drug for the treatment of M. marinum cutaneous

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02834.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

AbstractBackground.Lupus miliaris disseminatus faciei is a chronic inflammatory disorder, which affects adults of both sexes.Methods.This study included 25 patients with lupus miliaris disseminatus faciei. Three biopsies, representing early, fully developed, and late lesions, were taken from each patient.Results.Histopathologic examination of the different lesions revealed that in early lesions, all of them showed superficial perivascular and periappendigeal cellular infiltrate composed mostly of lymphocytes and few histiocytes with occasional neutrophils. The fully developed lesions showed a sarcoidal granuloma only (40%), sarcoidal granuloma with abscess (24%), sarcoidal granuloma around areas of caseation necrosis (20%), and a mixture of sarcoidal and tuberculoid granulomas (16%).Conclusions.All the late lesions showed extensive fibrosis especially in the perifollicular areas. Scattered lymphocytes, histiocytes and neutrophils were present within the fibrotic areas. A possible explanation of the pathogenesis is discussed.

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02835.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

摘要:

AbstractBackground.Cutaneous infection with Mycobacterium fortuitum, a ubiquitous rapid growing atypical mycobacterium, most often occurs as a postsurgical wound complication or at the site of a penetrating injury to the skin. Rarely, disseminated infection with cutaneous involvement can occur in immunocompromised patients.Case Report.A 47‐year‐old black woman presented with a 10‐year history of numerous draining abscesses and tender nodules on the back and buttocks unresponsive to oral and intravenous antibiotics. Biopsy showed a granulomatous and suppurative dermatitis and panniculitis and special stains did not reveal organisms. M. fortuitum was cultured from involved skin on two separate occasions. The patient improved with a 2‐week course of intravenous amikacin and cefoxitin combined with oral probenecid followed by a course of doxycycline and ciprofloxacin.Conclusions.Widespread primary cutaneous infection with M. fortuitum may occur in an immunocompetent patient. Chronic draining skin abscesses unresponsive to routine antibiotics may represent infection with an atypical mycobacterium; tissue cultures of affected skin should be performed to rule out this possibility. Therapy should be directed by culture sensitivity

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02836.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02837.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1993.tb02838.x

出版商:Blackwell Publishing Ltd    

年代:1993

数据来源: WILEY