ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03583.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03584.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03585.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03586.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03587.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

AbstractBackground.Psoriasis remains a chronic disease with lesions that are often extensive and disfiguring. While the potential for psychosocial morbidity and impairment are recognized, the literature remains equivocal with regard to the prevalence and degree of this impairment.Methods.The present study utilized a new questionnaire designed to assess the type and degree of psychosocial impairment present among psoriasis patients. The questionnaire was designed to assess major areas of psychosocial functioning and was completed by 64 patients undergoing outpatient treatment.Results.Approximately half the patients were found to have moderate to extreme levels of anxiety, depression, and anger. Patients reported experiencing these negative emotional sequelae both during their disease flares and during periods of remission. Patients were also found to have moderate to extreme levels of pruritus associated with their flares. Psychologic morbidity was positively associated with length of disease flare. Significant levels of social embarrassment, life disruption, and social withdrawal were found as well.Conclusions.Psoriasis does appear to cause significant psychosocial morbidity. Greater awareness by physicians and more comprehensive treatment addressing these psychosocial components may avert, or at least minimize, some of these negative sequelae.

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03588.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03589.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

AbstractBackground.The proliferation of non‐Langerhans cell histiocytes is a poorly understood process of unknown cause. Variation in the clinical features and/or histopathology of histiocytic proliferation has led to subclassification of the general category of non‐Langerhans cell histiocytes. Although the current classification may provide some useful generalizations in regard to the anticipated clinical course, wide variability in presentation and outcome make this classification less than optimal when dealing with individual patients. The objectives of the study were to present four cases of generalized non‐Langerhans cell histiocytosis.Materials and Methods.Medical records and slides of four patients diagnosed with non‐Langerhans cell histiocytosis at the Cleveland Clinic are reviewed.Results.The patients exhibit features of more than one subtype of non‐Langerhans cell histiocytosis.Conclusion.The overlap among the clinical and histologic features of the generalized cutaneous non‐Langerhans cell histiocytic disorders suggests that they represent one disease entity with a wide spectrum of presentations rather than many distinc

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03590.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03591.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1995.tb03592.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY