ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03649.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03650.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03651.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.Nodular fasciitis is a fibroblastic proliferation in which nodules, most commonly appearing on the extremities, develop suddenly and rapidly. Although excisional biopsy is curative, the nodules will often resolve spontaneously; however, the histologic appearance of a pleomorphic spindle cell neoplasm with frequent mitotic figures may raise concern of a more malignant neoplasm and lead to unnecessary and overly aggressive therapy.Methods.A case of nodular fasciitis presenting in an unusual location, intradermally at the lateral canthus, is discussed.Results.Review of the recent literature from other disciplines reveals new insights into the etiology and diagnostic options (fine needle aspiration, tomography, other imaging techniques) for this puzzling disease.Conclusions.When nodular fasciitis occurs in an unusual location, such as on the head and neck or at an intradermal location, it will not present as the deep, mobile, nontender nodule described in the dermatologic literature. Fine‐needle aspiration and modern imaging techniques may help in the diagnosis and prevent unnecessary surgery for a self‐limited condit

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03652.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.The sicca syndrome has been defined as the occurrence of xerostomia and xerophthalmia. Sjögren's syndrome is the most common cause of the sicca syndrome; however, these two syndromes are not synonymous and there are many potential etiologies of the sicca syndrome. A less known cause of sicca syndrome is amyloidosis that to date has only been reported in the nondermatology literature.Observations.A 79‐year‐old man with known amyloidosis presented with persistent xerostomia. He had the classic cutaneous findings of periorbital and “pinch” purpura. A labial biopsy showed diffuse deposition of amorphous eosinophilic material surrounding salivary acini. Apple‐green birefringence was noted with Congo red staining and the diagnosis was made of amyloidosis in the minor salivary glands causing xerostomia.Conclusions.The sicca syndrome can be caused by systemic amyloidosis. Because this fact is not in the dermatologic literature, many dermatologists are not aware of this uncommon presentation. The knowledge of the many causes of the sicca syndrome and an understanding of the differences between this and Sjögren's syndromes are important for any de

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03653.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.The clinical diagnosis of cutaneous leishmaniasis is confirmed by demonstrating the organism on a superficial smear or on a biopsy of the lesion. Misdiagnosis in a biopsy specimen may be due to scantyLeishmaniaorganisms that may not be identified in histologic sections.Methods.Punch biopsies of skin lesions, suspected clinically to be cutaneous leishmaniasis, from 29 patients were taken. Touch smears on slides were air‐dried, fixed with methyl alcohol, and stained with Giemsa stain. Results of routine histologic examination were then compared with those of touch preparation.Results.Twenty‐one cases were positive for leishmaniasis. In 18 cases, the organisms were seen both in the biopsy and in the touch preparation. In three cases, the organisms were only identified on touch preparation.Conclusions.A touch preparation improves the sensitivity of the diagnosis of cutaneous leishmaniasis without incurring additional cost to the laborat

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03654.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.While studying cutaneous leishmaniasis in the central part of western Venezuela, we found four cases of disseminated American cutaneous leishmaniasis, three from the Lara State and one from Portuguese State.Methods.A clinical history was taken for each of these patients, followed by microscopic examination of the Giemsa‐stained smears from their cutaneous lesions and by a Montenegro skin test. Serum from a skin lesion were grown in Novy‐MacNeal‐Nicolle medium (nnn). Hamsters were inoculated with suspension of tissues taken from the patient's lesions. Biopsies were taken for histopathologic examination. Isolates from cultures on nnn medium and from hamsters were subcultured in Schneider's medium for parasite identification, using molecular techniques. Treatment with injections of N‐methyl glucamine antimonate, 25 mg/kg/day was precribed for each patient for 20 consecutive days and, after a week of rest, a second course of injections was administered.Results.Patients had disseminated papular, ulcerous, nodular, and ulceronodular lesions on the skin. Smears of the skin lesions from all of the patients showed abundant amastigotes within histiocytes or free in the tissues. The skin test was negative in two patients. On histopathologic examination of skin lesions, mainly numerous vacuolated histiocytes filled with amastigotes were observed. Isolates from all the patients were identified asLeishmania venezuelensis.One of the patients healed after treatment with N‐methyl glucamine antimonate. The others were resistant to this therapy.Conclusions.Diffuse cutaneous leishmaniasis can be caused also byLeishmania venezuelensis.Patients with nodular lesions who presented a negative Montenegro skin test were more resistant to treatment with specific pentavalent an

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03655.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackgroundThe extent of the problem of cutaneous leishmaniasis in Jordan during the decade 1983 to 1992 was investigated.Methods.Data were collected from the dermatology departments and the laboratories of the Royal Medical Services and the Ministry of Health as well as from private dermatologists. Two thousand two hundred and ninety‐five cases were verified of whom men represented 80%. The majority (80%) were<25 years with the highest percentage (31%) occurring in the 16 to 20‐year age group.Results.The lowest number of cases was reported in June compared to the maximum in October, and the highest number recorded per year was 463 in 1992. For the decade, the Jordan Valley was the most important locality where 43% of the cases occurred.The incidence rate per 100,000 ranged from 1.89 in 1989 to 14.39 in 1984 and the period prevalence for the decade was 5.36 per 100,000. The time‐lag between the appearance of a lesion and the first diagnosis extended from 0 to 23 months with the average being 2 months. The number of lesions per patient ranged from one to 45; 24% were located on the face, 28% on the upper extremity, 36% on the lower extremity, and 12% on other sites.Conclusions.The factors that contributed to the findings include infected rodent, nonexposed army recruits and farm workers, land reclamatory and relaxation of preventative mea

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03656.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03657.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03658.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY