ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03891.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03892.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03893.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03894.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03895.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:A group of 140 cases of various forms of lupus erythematosus (LE) were examined for 24 variables, inducting the 11 criteria of the American Rheumatism Association (ARA) for the classification of systemic lupus erythematosus (SLE), and 13 additional criteria suggested by the European Academy of Dermatology and Venerology (EADV) for studies of cutaneous LE with or without systemic involvement. The EADV study factors included skin histopathology and immunopathology, complement and IgG levels, and other laboratory tests, as well as selected clinical findings, most notably the papulosquamous and/or annular lesions that characterize sub acute cutaneous LE (SCLE). The patients examined included 50 SLE, 35 SCLE, 30 discoid LE (DLE), 25 disseminated DLE (DDLE), and 17 polymorphous light eruption (PMLE) cases. Preliminary analyses of the data reveal the following: (1) The SCLE cases differed significantly from SLE, DLE, and DDLE in 10 of 11 ARA criteria (all but photosensitivity). (2) The frequencies of positive findings in SCLE also differed significantly for 11 of 13 EADV study factors. (3) While no significant differences appeared in the frequency of photosensitivity between the five study groups, photo‐testing revealed significant increases in the frequency of persistence of the photo reactions for 10 days and their Koebnerization in the SCLE cases. (4) The presence of SS‐A (Ro)/SS‐B (La) antibodies had some predictive value for the appearance of systemic involvement in SCLE, as seen by the increased frequencies of five or more ARA criteria, although highly significant differences from SLE occurred in the absence of renal involvement and lower frequency of ANA and LE band test. We conclude from these studies that the classification of the major forms of cutaneous LE, with and without systemic involvement, requires not only the ARA criteria, but also the examination of other factors such as those recommended by the EADV, and that the study groups should include SLE, SCLE, DLE, DDLE, and non‐LE controls such

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03896.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:Superficial granulomatous pyoderma, recently described as a variant of pyoderma gangrenosum, would be better termed pathergic granulomatous cutaneous ulceration as the seven previously described cases, as well as our own two cases, have significant dermal involvement histologically and heal with scarring. In contrast to pyoderma gangrenosum, lesions of superficial granulomatous pyoderma respond to less toxic anti‐inflammatory agent

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03897.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:To clarify the nosologic position of localized pretibial pemphigoid, Western immunoblotting analysis was carried out using the sodium dodecyl sulfate extracts of normal human epidermis. Sera from patients with localized pretibial pemphigoid and generalized bullous pemphigoid reacted with 220‐ to 240‐kd polypeptide, which is a critical point for a definite diagnosis of bullous pemphigoid. This result suggests that localized pretibial pemphigoid belongs to the same nosologic position as bullous pemphig

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03898.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:In a survey of dermatitis diagnosed in Lagos, Nigeria, dermatitis cruris pustulosa et atrophicans, lichen planus, lichen simplex chronicus, pretibial achromic lesions, and ichthyosiform dry skin are very common; necrobiosis lipoidica diabeticorum and diabetic dermopathy are moderately common; sporotrichosis and lichen amyloidosis are occasionally seen, but erythema nodosum is rare.

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03899.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:Cutaneous metastases occur in 2.5% to 5% of patients with malignant disease. The relative frequency of the primary site roughly parallels the frequency of the various malignancies in each sex. We present two cases of cutaneous malignancy occurring in a dermatomal distribution and masquerading as herpes zoster. The differential diagnosis of zosteriform eruptions is reviewed and the possible pathogenesis of metastatic disease in this cutaneous distribution is discussed. Skin biopsy is recommended in these cases to determine the etiology of the eruption.

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03900.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY