ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03483.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03484.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03485.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03486.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03487.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:Primary localized amyloidosis was found in a family. A 66‐year‐old woman had suffered from hoarseness for 18 years. A biopsy specimen from the larynx showed amyloid deposits in the submucosal connective tissue. Her 40‐year‐oid daughter noticed a subcutaneous nodule on her philtrum. Histologic examination showed the deposition of amyloid in the middle and lower dermis, which also encased the blood vessels and epidermal appendages. In both cases the amyloid deposits were positively stained with Congo red and the staining was resistant to potassium permanganate treatment. These amyloid deposits were strongly positive against the anti‐amyloid antibody of the λ light chain. These results indicate that the amyloid substance is derived from protein AL. There was no clinical or laboratory evidence of systemic amyloidosis or multiple myeloma in eith

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03488.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:Annular erythema developed in 22 patients with Sjögren syndrome. Clinically, the annular erythema was subdivided into three forms: Sweet disease‐like annular erythema with an elevated border (14 cases): subacute cutaneous lupus erythematosus (SCLE)‐like marginally scaled erythema (5 cases): and papular erythema (3 cases). Histopathologically, features commonly seen in annular erythema are deep perivascular and/or periappendageal infiltration of the lymphocytes with an admixture of neutrophils or plasma cells and less frequent epidermal changes suggestive of cutaneous lupus erythematosus. Immunoglobulin or complement deposition along the dermoepidermal junction of lesional skin was observed in 8 of 18 cases, and most of the dermal infiltrates consisted of CD4(+), 4B4(+) cells. The appearance of anti‐SS‐A(Ro) (100%) and anti‐SS‐B(La) (77%) was significantly higher in patients with annular erythema. These results suggest that patients with Sjögren syndrome might have a distinct annular erythematous lesion that is both clinically and histopathologically different from SCLE, although dose immunologic abnormalities exist in these

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03489.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:A 78‐year‐old man presented simultaneously with subacute cutaneous lupus erythematosus (SCLE) and Sweet syndrome (neutrophilic dermatosis). He was subsequently investigated for and found to have Sjögren syndrome. We believe that the simultaneous occurrence of the above cutaneous manifestations are very suggestive of and should prompt investigation for Sjögren syn

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03490.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

摘要:

Abstract:A case of Sweet syndrome in a patient with an acute myelomonocytic leukemia is reported, it is an unusual case simulating a facial erysipela. This case illustrates the difficulty in differentiating infection from Sweet syndrome in an immuno‐compromised patient. The negative cultures, ineffective antibiotics, and histopathologic examination results allowed the onset of corticosteroid therapy. The phagocytic function of the neutrophils studied by chemoluminescence was normal in the patient. The physiopathology of Sweet syndrome is discussed, in particular the role of cytokines in the accumulation of granulocyte

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03491.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1991.tb03492.x

出版商:Blackwell Publishing Ltd    

年代:1991

数据来源: WILEY