ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03558.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03559.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03560.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03561.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03562.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03563.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractThe authors describe ten cases of cutis marmorata telangiectatica congenita (CMTC). All of these cases were sporadic. The incidence of associated anomalies was relatively low, and three patients had skin manifestations (cutaneous atrophy and nevus telangiectaticus). In two patients, the right leg was shorter and thinner. Another two showed neurologic symptoms without lasting neurologic damage. New associated anomalies, such as tendinitis stenosans and bowing of the lower legs, did not provide additional information regarding the cause of CMTC. The authors suggest that Happle's lethal gene hypothesis for Klippel‐Trenaunay and Sturge‐Weber syndromes also could be applied to C

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03564.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractA comparative histopathologic study is made between the hypopigmented and hyperpigmented skin lesions of pityriasis versicolor and normal skin areas utilizing histochemical stains and electron microscopy. There were no differences found between the population of Dopa‐positive melanocytes within the hypopigmented and hyperpigmented lesions and the normal skin areas. The total epidermal pigmentation was diminished in hypopigmented lesions. The keratin layer was found to be significantly thicker in hyperpigmented lesions and contained more organisms. In hypopigmented lesions, melanocytes contained fewer and smaller melanosomes and exhibited signs of degenerative cellular change

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03565.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractForty‐eight patients with progressive systemic sclerosis (PSS) (man‐woman ratio, 7:41) were studied, and detailed questionnaires were used to clarify the relationship between occupational stresses and the initial signs of PSS. All of the patients were right‐handed. Raynaud sign was seen in 37 of the 48 patients (77.1%) as the predominant initial sign of PSS, and it first was noticed on the right index and middle fingers. Three sets of extrinsic aggravating factors, vibration stress, fine hand work with mental stress, and exposure to cold, were believed to be related closely to the development of the initial signs because the initial signs appeared after long‐term exposure to the extrinsic

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03566.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY

摘要:

AbstractBiopsy specimens of cutaneous discoid lesions of 71 patients with cutaneous lupus erythematosus (CLE) were studied. The material was examined by direct immunofluorescence (DIF) to establish positivity and morphologic patterns of immunoglobulins and complement deposits in the basement membrane zone (BMZ). A correlation between DIF results and thickening of the epidermis basement membrane (BM) stained by periodic acid‐Schiff (PAS), obtained from 31 matched biopsy specimens, also is presented. Direct immunofluorescence had positive results in 66.20% of the 71 examinations and 70.97% of the matched examinations, whereas PAS showed BM thickening in 100% of the specimens. This observation stresses the importance of such histopathologic findings in the diagnosis of discoid lesions in CLE. There was no correlation between DIF patterns and PAS‐stained BMZ thickening. These findings merit additional study. In conclusion, an accordance between PAS‐stained BM thickening and immunoglobulin deposits has occurred in 70.97% of cases. This phenomenon does not depend on the presence of immunocomplexes, for it occurs even in cases in which immunocomplex deposits were not det

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1992.tb03567.x

出版商:Blackwell Publishing Ltd    

年代:1992

数据来源: WILEY