ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04598.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04599.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04600.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04601.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04602.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04603.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT:The relationship between cutaneous malignant melanoma (MM) and possible risk factors was assessed in a case‐controlled study. Two hundred patients and 200 non‐melanoma controls of German origin matched for age and sex were interviewed and examined for pigmented moles and pigmentation characteristics. In patients with MM significantly more melanocytic nevi ≥ 2 mm (MCN) were found (mean, 53 MCN) compared to control cases (mean, 18 MCN). For persons with>60 MCN the relative risk (RR) for developing MM increased 15 times compared to ≤ MCN. Additional independent markers for an increased risk were presence of atypical MCN (RR = 7 vs. none) found in 45% of patients and in 5% of the control group, moderate to large numbers of actinic lentigines (RR = 6.2 vs. none), and lack of tanning as well as a tendency to sunburn (skin type I; RR = 2.2 vs. skin type IV) No significant correlation was found between the relative risk for MM and hair color, eye color, duration of free time sun exposure and number of sunburns. Individuals with permanent outdoor profession and sun exposure, however, showed a clearly increased relative risk for develo

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04604.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT:The causes of death of 50 patients who had had lichen planus have been investigated and compared with those of 50 patients with psoriasis and with those of the general population. Patients with lichen planus were as old as those with psoriasis and in the general population at the time of death, but the diseases causing death differed. Malignant tumors, particularly those of the gut and the bladder, and malignant hemopathies exceeded the expected prevalence. In addition, autoimmune diseases were more common than in patients with psoriasis and in the general population. Multiple sclerosis and primitive pulmonary fibrosis have never been described before in patients with lichen planus.

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04605.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT:A higher risk of reproductive system disorders, (which include benign tumors, endometriosis, dilation and curettage, hysterectomy, and other disorders requiring gynecologic biopsies) exist among women with cutaneous melanoma as compared to women with skin cancers: The odds ratio (OR) is 3.2, 95% confidence limits (1.0,10.1), p = 0.049; as compared to a random sample of women with no melanoma or skin cancers, the OR is 3.9, 95% confidence limits (1.2, 12.4), p = 0.021. Confirming the observations of others, the authors found that melanoma was associated with red hair. The data also confirmed the finding that melanoma is associated with significantly fewer pregnancies. The mean numbers of pregnancies in the melanoma group is 1.83 ± 1.6 (mean and standard deviation) compared to 2.99 ± 1.9 in the skin cancer group and 2.93 ± 1.9 in the random sample (p ≤ 0

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04606.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY

摘要:

ABSTRACT:Bowen's disease frequently has been reported to be associated with internal malignancy, although this association has been extremely controversial. The present study uses the technique of meta‐analysis to address this issue by pooling the results of the 12 studies published in the English‐language literature that previously have attempted to study this issue. The results indicated no significant association between the two conditions (chi square, 1 d.f., = 0.128, p>0.05, 95% confidence interval = 0.105–0.1503). Clearly, no extensive investigation in patients having Bowen's disease is warr

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1989.tb04607.x

出版商:Blackwell Publishing Ltd    

年代:1989

数据来源: WILEY