ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02579.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02580.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02581.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02582.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02583.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Abstract:Many diseases are peculiar to the black race and most practicing physicians in Africa have limited access to histopathologists, therefore, diagnosis is largely clinical. A retrospective study of 10,000 consecutive patients seen at the skin clinic of the Lagos University Teaching Hospital, Nigeria, was conducted with the objective of identifying the notable dermatoses affecting various parts of the body. The face and the shins were observed to have a very broad spectrum of dermatoses. Useful clinical descriptions of these dermatoses are highlighted in a three part paper to help practicing physicians.

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02584.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Abstract:A 79‐year‐old man had generalized humping of the nails and subungual tumors involving several fingers and the left big toe. Findings on histologic study of the tumor, together with the pattern on the peripheral blood smear, established the diagnosis of chronic lymphocytic leukemia. To the best of our knowledge, this is the first reported case of chronic lymphocytic leukemia involving the subungual area. The authors' observation emphasizes the importance of taking a biopsy specimen in the differential diagnosis of subungual tum

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02585.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Abstract:Patients treated with chronic disabling psoriasis often have psychosocial concerns that need to be addressed. The weekly patient support group at Stanford, led by a psychiatrist, is an integral part of the Psoriasis Day Care program. Although not considered group therapy in the traditional sense due to its self‐selective nature, the support group aims to reduce feelings of isolation and to enhance coping skills and self‐efficacy. In this setting, patients explore their feelings about psoriasis enabling them to better adapt to a visible disease. Common topics for discussion include lifestyle changes, stressful relationships, associated emotional reactions, occupational limitations, and treatment concerns. Components of the Psoriasis Day Care Center that enhance treatment response and responsibility for self‐care include: health education, psychosocial support systems, stress reduction, and enhanced coping skills acquired through shared experiences with other patients and medical pers

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02586.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Abstract:Eleven patients with systemic sclerosis (SSc) were studied for plasma and cutaneous fibrinolytic activity, residual (potential fibrinolysis) fibrinolytic activity (FA) of the dermal vessels that is related to the endothelial storage of plasminogen activators that become available due to particular stimuli such as intradermic injection of histamine, and the serum levels of circulating von Willebrand antigen, antithrombin III, plasminogen, (β‐thromboglobulin, and platelet aggregate ratio (PAR). Cutaneous FA (autohistographic fibrin film method) appeared normal or increased in non‐affected skin, normal in lesional skin, and increased after intradermal (i.d.) injection of 0.1 ml of 0.01% histamine. Monoclonal antibodies directed against the catalytic site of tissue type plasminogen activator completely blocked the fibrinolytic activity, while anti‐urokinase antibodies did not abolish the lysis areas. Plasmatic FA, euglobulin lysis time test, (ELT) and the levels of β‐thromboglobulin resulted similar to the controls. A significant increase in von Willebrand Factor VIII antigen (but not of Factor VIII coagulant) was observed in the patients (p<0.01). Platelet aggregate ratio, levels of plasma plasminogen and Antithrombin III showed a significant difference (p<0.01) when compared with the control subjects. Data suggest that primary injured microvessels in SSc are likely to be arteriolae while venulae could be affected by secondary hypoxia due to the arteriolar damage with consequent release of tissue type plasminogen activator. Therefore, the authors suggest that the fibrinolytic potential is maintained in SSc and that the fibrinolytic therapy should not be used in all patients with SSc but only in those cases with documented exhaustion of plasmatic and/or cut

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02587.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1990.tb02588.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY