ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03681.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03682.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03683.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03684.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.Behçet's disease is a chronic, recurrent, inflammatory disorder characterized by the triad of oral and genital ulcers and ocular lesions. The etiology is unknown. This is the first report giving details of the clinical manifestations of Behçet's disease in Jordanian patients.Methods.Twenty patients with Behçet's disease were studied to determine the clinical pattern in the North of Jordan. The patients were seen in Princess Basma Teaching Hospital in North Jordan. They presented to various clinics and underwent full clinical examination. Data for each patient on all features of Behçet's disease were recorded on a standard form. A comparison was made between Behçet's disease in Jordan and other countries in the region.Results.Of the 20 patients, 14 were men and six women, giving a ratio of 2.3:1. Their ages ranged from 14 to 58 years. All had mouth ulcers, 65% genital ulcers, 65% ocular involvement, 55% joint involvement, 35% skin lesions, 20% vascular lesions, and 5% gastrointestinal involvement. The oral ulcers were the first manifestation of the disease process in 70% of our patients. Skin lesions, genital ulcers, and involvement of the central nervous system and the pulmonary system were less frequent in our study.Conclusions.Although it is difficult to obtain figures as to the incidence and prevalence of Behçet's disease in Jordan, the clinical manifestations, with a few exceptions, are similar to those in other countries in the r

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03685.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground and Objective.Papular‐purpuric gloves‐and‐socks syndrome (PPGSS) is a recently described dermatosis in which human parvovirus B19 (HPV B19) has been implicated as etiologic agent; however, it is suspected that PPGSS may be caused by various agents. This study was designed to survey the general characteristics of PPGSS and to determine the role of HPV B19 in its etiology.Methods.We analyzed data from 21 patients and examined serum samples from three new cases for various viruses.Results.The PPGSS displays a striking uniform clinical pattern. Histologic and immunofluorescence findings are nonspecific. Seroconversion of HPV B19 was reported in six cases and confirmed in two of our patients. In only one case was a possible causative role ofCoxsackie virusB6 suggested consistently.Conclusions.The PPGSS represents a distinctive dermatosis and a manifestation of HPV B19 infection. Unlike erythema infectiosum, anti‐HPV B19 antibodies seem to develop later after onset of the skin eruption and while viremia is still

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03686.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.Many skin diseases in developing countries are associated with socioeconomic factors. It is generally agreed that a public health approach to dermatology in this setting is particularly appropriate; but, there has been little epidemiologic research done to examine which particular socioeconomic factors are important determinants of the prevalence of skin disease. This is especially true in sub‐Saharan Africa.Methods.A survey of two villages in Ngara district, North West Tanzania, involved 254 randomly selected households using a questionnaire, measurements of houses and water quality, and examination of the skin of 1114 household members.Results.Significant skin disease was encountered in 300 individuals (26.9%). Transmissible diseases comprised the bulk of skin disease (73.9%) with younger age groups being affected most. Socioeconomic conditions were poor, with low quality, crowded housing, low levels of literacy, unsatisfactory water sources, and few households with a regular cash income. Household density was significantly associated with transmissible skin disease. Other indicators of poverty (e.g., no regular cash income and illiteracy) did not correlate with the prevalence of skin disease.Conclusions.Skin disease was highly prevalent in the villages surveyed, especially transmissible diseases in the younger age groups. Household density was the only socio‐economic factor significantly associated with skin disease. Reduction of household density is an attainable intervention that could reduce the prevalence of skin disease in rural African populations. Simple studies like this one should be the first step in community dermatology, assessing the burden of skin disease in communities and looking for particular factors with which public health interventions could effectively reduce the prevalence of skin dise

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03687.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.Skin disease is a common problem, accounting for significant morbidity in developing countries. Knowledge about the prevalence of different skin conditions allows appropriate planning for provision for these health needs. There are currently few data about the needs in rural areas; therefore, this study was set up to investigate skin abnormalities found in a village population in Tanzania.Materials and Methods.A village with a population of 2,876 was chosen and one‐third of the population was examined for cutaneous abnormalities.Results.During the survey, 97.7% of the target population was examined. Signs of nutritional deficiency were common with koilonychia affecting 18.1% of the population examined and signs of hypoproteinemia being present in 3.4% of them. Infections and infestations were also frequently seen. Scabies was observed in 6.0% and pediculosis capitis in 5.3%. Dermatophyte infection was present in 5.1%. These were all most common in prepubertal children. Leg sores were seen in 5.1% and leg ulcers in 3.0% of the population.Conclusions.The survey reveals that easily treatable skin infections and infestations are common in a rural Tanzian population. Signs of nutritional deficiency are also frequently see

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03688.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

摘要:

AbstractBackground.Chloracne is a disease associated with toxicity of halogenated compounds used in some industrial processes. A patient affected by chloracne led us to study a total of nine cases from a single factory.Methods.We studied the clinical features of nine patients exposed chronically to chlorobenzenes. On all of them blood samples were drawn and biopsies of affected skin and liver were taken. Their work environment was visited and studied.Results.All nine patients were men and had polymorphic skin lesions, characterized mainly by comedones and cysts. They had chronic conjunctivitis and seven had cysts in the Meibomian glands. All of them had polyneuropathy and liver damage and seven had hypertriglyceridemia. Compounds known to cause chloracne were found in exceedingly high concentrations in the water used in the workplace.Conclusions.Every patient exposed to halogenated compounds with the cutaneous manifestations of chloracne should be carefully investigated for systemic complications (such as ophthalmic, neuropathic, hepatic, and lipoprotein abnormalities).

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03689.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY

ISSN:0011-9059    

DOI:10.1111/j.1365-4362.1996.tb03690.x

出版商:Blackwell Publishing Ltd    

年代:1996

数据来源: WILEY