摘要:

Eight patients with skin lesions attributed to methylmercury exposure are reported. The outbreak of poisoning occurred in Iraq as a result of the handling and ingestion of treated grain find home‐made bread. The skin manifestations were rather rare and varied in severity and histological appearanc

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03623.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Three printers showed a contact sensitization to the Letterflex® urethane photoprepolymer mixture. The technical chemistry of this new printing procedure is described

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03624.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Over 700 patients were screened by patch testing for sensitivity to the components of a vehicle from July 1974 through June 1976 the Mayo Clinic. A modified version of the vehicle tray originally suggested by Fisher et al. (1971) was used, containing 14 substance commonly found in vehicles. Patches were applied for 24 rather than the usual 48 hours. Our percentage of reactivity compares favorably with the 48‐h application method, thus demonstrating the efficacy of this time‐saving technique. The method and usefulness of determining a percentage of irritancy are discussed. This was found to be a valuable tool in assessing false‐positive reactions among our percentage of reactivity. Four irritants were demonstrated: phenylmercuric acetate (0,05 % pet.), sodium lauryl sulfate 1 % aq), thimerosal (0.1 % aq) and hexachlorophene (1 %

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03625.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Experimental phytophotodermatitis was produced using crushed leaves from the gas plant,Dictamnus albus.The tests were made using the chamber method and irradiated with ordinary black light tubes.An occlusion time of not less than 30 min was needed to give a phototoxic reaction in all test subjects. An occlusion time 30–120 min gave the optimal results, but contact for 24 h produced only weak and inconsistent reactions.The phototoxic substance was readily absorbed into the skin within 10–15 min. The phototoxic tendency already began to disappear within 30 min after the tests were removed.UVA energy of 0.3 J/cm2was enough to evoke a phytophotoreaction in all of the test subjects when other conditions were optimal.The reactions were enhanced by adding water to the test sites.Deep‐freezing of the plant material did not destroy the phototoxicity within a 4‐month

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03626.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Fifty normal control volunteers were patch tested to 20% neomycin as well as tobramycin 1%, 10%, 20% and 30% in white petrolatum. Tobramycin is a new aminoglycoside antibiotic for prescription Ophthalmologic use in the United States.There were no reactions on any of the control volunteers.Twenty known and proven neomycin‐allergic patients were then tested to tobramycin 10 % and 20 % in white petrolatum, as well as to neomycin 20 % aqueous and 20 % in white petrolatum.All 20 reacted with a 2+ or greater response to the neomycin patch tests. Twelve out of the 20 or 60 % of the neomycin‐allergic patients reacted to the 10 % tobramycin in white petrolatum. Thirteen out of 20 or 65 % reacted to 20 % tobramycin in while petrolatum.From these data, tobramycin (ophthalmic) should not be used to treat known neomycin‐allergic patients without first patch tolling the patient with 20 % tobramycin in white petrolatum. It appears probable that 65 % of neomycin‐allergic patients would react with a dermatitic response to such

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03627.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Patch tests repeated one or more times over periods of up to 3 years in 208 subjects with allergic contact dermatitis produced evidence of persistent specific sensitivities in almost 50% of cases. In about 25% the reactivity disappeared and over 25 % developed new sensitivities. No new sensitivities appeared in 253 patients with non‐allergic contact dermatitis or with other types of dermatitis in whom the same patch tests were carried out.The history and follow‐up of patients with new sensitivities brought into focus the presumed actiopathogenetic role of further contacts, especially occupational or after topical applications. Patch tests themselves, provided the correct technique is employed especially as regards the concentration of allergens, do not seem to be responsible for new sensitizations to any significant ext

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03628.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

An outbreak of rubber fingerstall dermatitis in a Danish post office was found to be caused by minute amounts of isopropylphenyl‐para‐phenylenediamine (IPPD) in the fingerstalls. The presence of IPPD in the fingerstalls could not be explained by the manufacturer and had to be confirmed by gas chromatographic analy

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03629.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Industrial injuries and disablement benefits paid for industrial dermatitis (PD 42) in Northern Ireland are analyzed by age, industry and substance responsible. The most significant trend is a decrease in the number of cases due to cement and an increase in the number of nickel cases.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03630.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

A patient suffering from an eczema of the right hand showed after routine patch testing an immediate urticarial reaction to cinnamaldehyde.The same reaction could be noted in three out of eight control persons. Laboratory investigations revealed cinnamaldehyde to have a histamine liberating effect, a fact not previously mentioned in reports on untoward reactions to this compound.

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03631.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY

摘要:

Sixteen taxa of the genusPartheniumfrom North and South America and 20 sesquiterpene lactones derived from plants of the Compositae family were used for patch testing six volunteers who were known to be contact sensitive to plants and lactones of this family. The patterns of cross‐sensitivity and structure‐activity relationships of the allergenic lactones are evaluated and the clinical and ecological relevance is discus

ISSN:0105-1873    

DOI:10.1111/j.1600-0536.1977.tb03632.x

出版商:Blackwell Publishing Ltd    

年代:1977

数据来源: WILEY